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MBTPS1 Antibody (2E6)

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Immunocytochemistry/ Immunofluorescence: MBTPS1 Antibody (2E6) [H00008720-M07] - Analysis of monoclonal antibody to MBTPS1 on HeLa cell. Antibody concentration 10 ug/ml
ELISA: MBTPS1 Antibody (2E6) [H00008720-M07] - MBTPS1 Antibody (2E6) [H00008720-M07] - Detection limit for recombinant GST tagged MBTPS1 is 0.1 ng/ml as a capture antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, ICC/IF
Clone
2E6
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

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MBTPS1 Antibody (2E6) Summary

Description
Quality control test: Antibody Reactive Against Recombinant Protein.
Immunogen
MBTPS1 (NP_957720.1, 246 a.a. ~ 355 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. GLGHGTFVAGVIASMRECQGFAPDAELHIFRVFTNNQVSYTSWFLDAFNYAILKKIDVLNLSIGGPDFMDHPFVDKVWELTANNVIMVSAIGNDGPLYGTLNNPADQMDV
Specificity
Reacts with membrane-bound transcription factor peptidase, site 1.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
MBTPS1
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
Application Notes
This antibody is reactive against recombinant protein in ELISA.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for MBTPS1 Antibody (2E6)

  • EC 3.4.21.112
  • Endopeptidase S1P
  • KIAA0091
  • KIAA0091MGC138712
  • MBTPS1
  • membrane-bound transcription factor peptidase, site 1
  • membrane-bound transcription factor protease, site 1
  • PCSK8
  • S1P
  • S1PMGC138711
  • SEDKF
  • site-1 protease
  • SKI1
  • SKI-1
  • SKI-1membrane-bound transcription factor site-1 protease
  • subtilisin/kexin isozyme-1
  • Subtilisin/kexin-isozyme 1

Background

The encoded protein has a central role in the regulation of lipid metabolism in cells. It is a sterol-regulated subtilisin-like serine protease that cleaves ER membrane-bound sterol regulatory element-binding proteins (SREBPs), a reaction that initiates the two-step proteolytic process by which transcriptionally active fragments of SREBPs are released from the membrane for translocation to the nucleus. The gene product is an integral membrane ER protein, with the bulk located in the ER lumen. It is synthesized as an inactive preproprotein that is self-activated by an intramolecular cleavage that generates the mature protein. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol MBTPS1
Entrez