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LL-37 Antibody (B-L47) [DyLight 680]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Clone
B-L47
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 680

Order Details

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LL-37 Antibody (B-L47) [DyLight 680] Summary

Immunogen
Human antimicrobial peptide LL-37. Hybridoma: Myeloma X63/AG.8653 x Balb/c node cells
Specificity
Recognizes both natural and recombinant human LL-37
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CAMP
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for LL-37 Antibody (B-L47) [DyLight 680]

  • 18 kDa cationic antimicrobial protein
  • Antibacterial peptide FALL-39
  • CAP18
  • CAP-18
  • cathelicidin antimicrobial peptide
  • CRAMP
  • epididymis secretory sperm binding protein
  • FALL-39 peptide antibiotic
  • FALL39
  • FALL-39
  • hCAP-181
  • HSD26
  • LL37

Background

Cathelicidins are a family of antimicrobial proteins predominantly found in the peroxidase negative granules of neutrophils. The cathelicidins are synthesized as preproproteins. Within the neutrophils, they are stored in granules as inactive proforms after removal of the signal peptide. The active biologic domains of the cathelicidins generally reside in the C terminus. The C terminal antimicrobial peptides are activated when cleaved from the proforms of the cathelicidins by serine proteases from azurophil granules. FUNCTION: Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity. SUBCELLULAR LOCATION: Secreted. TISSUE SPECIFICITY: Expressed in bone marrow and testis and neutrophils.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Additional LL-37 Products

Array NBP3-18121FR

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Bioinformatics

Gene Symbol CAMP