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LL-37 Antibody (B-L47) [Alexa Fluor® 350]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Clone
B-L47
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 350

Order Details

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LL-37 Antibody (B-L47) [Alexa Fluor® 350] Summary

Immunogen
Human antimicrobial peptide LL-37. Hybridoma: Myeloma X63/AG.8653 x Balb/c node cells
Specificity
Recognizes both natural and recombinant human LL-37
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CAMP
Purity
Affinity purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Affinity purified

Notes



Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for LL-37 Antibody (B-L47) [Alexa Fluor® 350]

  • 18 kDa cationic antimicrobial protein
  • Antibacterial peptide FALL-39
  • CAP18
  • CAP-18
  • cathelicidin antimicrobial peptide
  • CRAMP
  • epididymis secretory sperm binding protein
  • FALL-39 peptide antibiotic
  • FALL39
  • FALL-39
  • hCAP-181
  • HSD26
  • LL37

Background

Cathelicidins are a family of antimicrobial proteins predominantly found in the peroxidase negative granules of neutrophils. The cathelicidins are synthesized as preproproteins. Within the neutrophils, they are stored in granules as inactive proforms after removal of the signal peptide. The active biologic domains of the cathelicidins generally reside in the C terminus. The C terminal antimicrobial peptides are activated when cleaved from the proforms of the cathelicidins by serine proteases from azurophil granules. FUNCTION: Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity. SUBCELLULAR LOCATION: Secreted. TISSUE SPECIFICITY: Expressed in bone marrow and testis and neutrophils.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Additional LL-37 Products

Array NBP3-18121AF350

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Bioinformatics

Gene Symbol CAMP