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Latrophilin 2/LPHN2 Antibody

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Immunohistochemistry-Paraffin: Latrophilin 2/LPHN2 Antibody [NBP3-41181] - Used in DAB staining on fromalin fixed paraffin- embedded Kidney tissue
Immunohistochemistry-Paraffin: Latrophilin 2/LPHN2 Antibody [NBP3-41181] - Used in DAB staining on fromalin fixed paraffin- embedded Kidney tissue
Western Blot: Latrophilin 2/LPHN2 Antibody [NBP3-41181] - Sample: Recombinant protein.

Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications WB, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

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Latrophilin 2/LPHN2 Antibody Summary

Immunogen
Immunized with recombinant Rat Latrophilin 2/LPHN2 (Uniprot#: O88923; Val139-Pro398 (Uniprot#: O88923)
Clonality
Polyclonal
Host
Rabbit
Gene
ADGRL2
Purity
Antigen and protein A Affinity-purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 5-20ug/mL
  • Immunohistochemistry 5-20ug/mL
  • Western Blot 0.5-2ug/mL

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
0.01M PBS, pH7.4, 50% glycerol
Preservative
0.05% Proclin 300
Concentration
0.5 mg/ml
Purity
Antigen and protein A Affinity-purified

Alternate Names for Latrophilin 2/LPHN2 Antibody

  • ADGRL2
  • Calcium-independent alpha-latrotoxin receptor 2
  • CIRL2
  • CIRL-2
  • CL2
  • KIAA0786
  • Latrophilin 2
  • Latrophilin homolog 1
  • latrophilin homolog 2 (cow)
  • latrophilin-2
  • LEC1
  • LEC1LPHH1latrophilin 1
  • lectomedin-1
  • LPHH1
  • LPHN2

Background

Latrophilin-2 is an Orphan-B Receptor that binds alpha-latrotoxin, a potent presynaptic neurotoxin present in the venom of the black widow spider, in a Ca2+-independent manner. As with the other two latrophilins, it shares homology with lectin, olfactomedin, and transmembrane domains, and possesses variable C-termini and various alternative-splice sites. Latrophilin-2 is endoproteolytically cleaved at the end of the GPS domain, and the two subunits remain non-covantely linked as a heterodimer. Latrophilin-2 has been reported to be expressed in brain, breast, placenta, kidney, spleen, ovary, heart, and lung. ESTs have been isolated from a wide variety of tissue libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol ADGRL2