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LAMP Recombinant Protein Antigen

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Summary
Reactivity HuSpecies Glossary
Applications AC

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LAMP Recombinant Protein Antigen Summary

Description
A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human LAMP.

Source: E. coli

Amino Acid Sequence: VTNASLVLFRPGSVRGINGSI

Fusion Tag: N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

This product is intended to be used as a blocking antigen for antibody competition assays. Any other use of this antigen is done at the risk of the user. The use of this product for commercial production is strictly prohibited. Please contact technical support if you have any questions.
Source
E. coli
Protein/Peptide Type
Recombinant Protein Antigen
Gene
LSAMP
Purity
>80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

Dilutions
  • Antibody Competition 10 - 100 molar excess
Application Notes
This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP2-55960.

It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.

For current lot information, including availability, please contact our technical support team click nb-technical@bio-techne.com

Theoretical MW
20 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS and 1M Urea, pH 7.4.
Preservative
No Preservative
Purity
>80% by SDS-PAGE and Coomassie blue staining

Alternate Names for LAMP Recombinant Protein Antigen

  • FLJ34254
  • FLJ35396
  • IgLON family member 3
  • IGLON3FLJ54658
  • LAMP
  • LAMPFLJ37216
  • limbic system-associated membrane protein
  • LSAMP

Background

LSAMP, also known as Limbic system-associated membrane protein, is a 338 amino acid protein that is 53 kDa, expressed on limbic neurons and fiber tracts as well as in single layers of the superior colliculus, spinal cord and cerebellum; mediates selective neuronal growth and axon targeting, contributes to the guidance of developing axons and remodeling of mature circuits in the limbic system, vital for normal growth of the hyppocampal mossy fiber projection. Current research is being performed on several diseases and disorders including neuronitis, clear cell renal cell carcinoma, bipolar disorder, osteosarcoma, renal cell carcinoma, cerebritis, schizophrenia, and carcinoma. This protein has been shown to interact with PPNP, YWHAB, PPP2CB, DHX9, and STX16 in cell adhesion and nervous system development pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol LSAMP