Quality control test: Antibody Reactive Against Recombinant Protein.
Immunogen
KLF11 (NP_003588, 404 a.a. ~ 512 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. TYFKSSHLKAHLRTHTGEKPFNCSWDGCDKKFARSDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMTTKKIPGWQAEVGKLNRIASAESPGSPLVSMPASA
Specificity
KLF11 - Kruppel-like factor 11 (10D8)
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
KLF11
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for IF, ELISA, ChIP and IHC-P. Use in Immunoprecipitation reported in scientific literature (PMID: 23408111).
Reviewed Applications
Read 1 Review rated 4 using H00008462-M03 in the following applications:
Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.
Packaging, Storage & Formulations
Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
IgG purified
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for KLF11 Antibody (10D8)
FKLFFKLF1
Krueppel-like factor 11
Kruppel-like factor 11
MODY7TGFB-inducible early growth response protein 2
TIEG-2
TIEG2TGFB inducible early growth response 2
Tieg3
Transforming growth factor-beta-inducible early growth response protein 2
Background
Transcription factor. Activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding inhibiting cell growth. Represses transcription of SMAD7 which enhances TGF-beta signaling. Induces apoptosis
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Lin L The role of Tumor-associated Macrophages (TAMs) and Transcription Factor KLF11 in breast cancer (BC) and KLF11-mediated Transcriptional Regulation of BC-associated TAMs Thesis 2022-01-01 (ICC/IF, IF/IHC, Human)
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