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Kallikrein 4/Prostase/EMSP1 Antibody (KLK4/8942)

Images

 
Formalin-fixed, paraffin-embedded human skin stained with Kallikrein 4/Prostase/EMSP1 Antibody (KLK4/8942). HIER: Tris/EDTA, pH9.0, 45min. 2°C: HRP-polymer, 30min. DAB, 5min.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
KLK4/8942
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
0.2 mg/ml

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Kallikrein 4/Prostase/EMSP1 Antibody (KLK4/8942) Summary

Description
Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C. Non-hazardous. No MSDS required.
Immunogen
Recombinant fragment of human Kallikrein 4/Prostase/EMSP1 protein (around aa 1-200) (exact sequence is proprietary)
Localization
Secreted
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
KLK4
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 1-2ug/ml for 30 minutes at RT
Application Notes
Immunohistochemistry-Paraffin 1-2ug/ml for 30 minutes at RT. Optimal dilution for a specific application should be determined.. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes

Packaging, Storage & Formulations

Storage
Store at 4C.
Buffer
10mM PBS with 0.05% BSA
Preservative
0.05% Sodium Azide
Concentration
0.2 mg/ml
Purity
Protein A or G purified

Alternate Names for Kallikrein 4/Prostase/EMSP1 Antibody (KLK4/8942)

  • AI2A1
  • ARM1
  • EC 3.4.21
  • EC 3.4.21.-
  • EMSP
  • EMSP1
  • EMSP1MGC116827
  • Enamel matrix serine proteinase 1
  • kallikrein 4 (prostase, enamel matrix, prostate)
  • Kallikrein 4
  • kallikrein-4
  • Kallikrein-like protein 1
  • kallikrein-related peptidase 4
  • KLK4
  • KLK-L1MGC116828
  • Prostase
  • PRSS17enamel matrix serine protease 1
  • PSTSandrogen-regulated message 1
  • Serine protease 17

Background

Kallikreins are a subgroup of serine proteases and are implicated in carcinogenesis. The novel KLK gene, KLK-L4, is expressed in a variety of tissues including prostate, salivary gland, breast, and testis. Its expression is regulated by steroid hormones in breast cancer cell lines may be involved in the pathogenesis and/or progression of breast cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Kallikrein 4/Prostase/EMSP1 Antibody (NBP3-26759) (0)

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol KLK4