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Kallikrein 3/PSA Antibody (A67-B/E3 + 1A7) [Janelia Fluor® 585]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, ICC/IF, IHC, ICC/IF
Clone
A67-B/E3 + 1A7
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 585

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-11483AF350
Alexa Fluor 405
NBP3-11483AF405
Alexa Fluor 488
NBP3-11483AF488
Alexa Fluor 532
NBP3-11483AF532
Alexa Fluor 594
NBP3-11483AF594
Alexa Fluor 647
NBP3-11483AF647
Alexa Fluor 700
NBP3-11483AF700
Alexa Fluor 750
NBP3-11483AF750
Allophycocyanin
NBP3-11483APC
Biotin
NBP3-11483B
CoraFluor 1
NBP3-11483CL1
DyLight 350
NBP3-11483UV
DyLight 405
NBP3-11483V
DyLight 488
NBP3-11483G
DyLight 550
NBP3-11483R
DyLight 594
NBP3-11483DL594
DyLight 650
NBP3-11483C
DyLight 680
NBP3-11483FR
DyLight 755
NBP3-11483IR
FITC
NBP3-11483F
HRP
NBP3-11483H
Janelia Fluor 525
NBP3-11483JF525
Janelia Fluor 549
NBP3-11483JF549
Janelia Fluor 635
NBP3-11483JF635
Janelia Fluor 646
NBP3-11483JF646
Janelia Fluor 669
NBP3-11483JF669
PE
NBP3-11483PE
PerCP
NBP3-11483PCP
Unconjugated
NBP2-44889-0.1mg
mFluor Violet 450 SE
NBP3-11483MFV450
mFluor Violet 500 SE
NBP3-11483MFV500
mFluor Violet 610 SE
NBP3-11483MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-44889-0.1mg
IHC-Prediluted
NBP2-48334
Azide and BSA Free
NBP3-11483
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Kallikrein 3/PSA Antibody (A67-B/E3 + 1A7) [Janelia Fluor® 585] Summary

Immunogen
Kallikrein 3/PSA from human sperm plasma (Uniprot: P07288)
Localization
Cytoplasmic
Specificity
Recognizes a single protein of 33-34kDa, identified as the prostate specific antigen (PSA). This monoclonal antibody is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia.
Isotype
IgG1 Kappa/IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
KLK3
Purity
Protein A or G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Kallikrein 3/PSA Antibody (A67-B/E3 + 1A7) [Janelia Fluor® 585]

  • APS seminin
  • EC 3.4.21
  • EC 3.4.21.77
  • Gamma-seminoprotein
  • hK3
  • Kallikrein 3
  • kallikrein 3, (prostate specific antigen)
  • Kallikrein-3
  • kallikrein-related peptidase 3
  • KLK2A1
  • KLK3
  • P-30 antigen
  • prostate specific antigen
  • prostate-specific antigen
  • PSA semenogelase
  • PSA
  • Semenogelase
  • Seminin

Background

PSA is a chymotrypsin-like serine protease (kallikrein family) produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liverderived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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PAPOLA Antibody
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TUSC2 Antibody -
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Kallikrein 3/PSA
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NBP3-11483JF585
Kallikrein 3/PSA Antibody (A67-B/E3 + 1A7) [Janelia Fluor® 585]
Species: Hu
Applications: Flow, ICC/IF, IHC, ICC/IF

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Bioinformatics

Gene Symbol KLK3