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Jagged 2 Antibody (746513) [Janelia Fluor® 646]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
746513
Clonality
Monoclonal
Host
Rat
Conjugate
Janelia Fluor 646

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB4748U-100UG
Alexa Fluor 405
FAB4748V-100UG
Alexa Fluor 488
FAB4748G-100UG
Alexa Fluor 532
FAB4748X
Alexa Fluor 594
FAB4748T-100UG
Alexa Fluor 647
FAB4748R-100UG
Alexa Fluor 700
FAB4748N-100UG
Alexa Fluor 750
FAB4748S-100UG
Allophycocyanin/Cy7
FAB4748APCCY7
Biotin
FAB4748B
CoraFluor 1
FAB4748CL1
DyLight 350
FAB4748D
DyLight 405
FAB4748E
DyLight 488
FAB4748K
DyLight 550
FAB4748L
DyLight 594
FAB4748M
DyLight 650
FAB4748W
DyLight 680
FAB4748Y
DyLight 755
FAB4748Z
FITC
FAB4748F
HRP
FAB4748H
Janelia Fluor 525
FAB4748JF525
Janelia Fluor 549
FAB4748I
Janelia Fluor 585
FAB4748JF585
Janelia Fluor 635
FAB4748JF635
Janelia Fluor 669
FAB4748JF669
PE/Atto594
FAB4748PEATT594
PE/Cy5.5
FAB4748PECY55
PE/Cy7
FAB4748PECY7
PerCP
FAB4748C
Unconjugated
MAB4748
mFluor Violet 450 SE
FAB4748MFV450
mFluor Violet 500 SE
FAB4748MFV500
mFluor Violet 610 SE
FAB4748MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB4748
Carrier Free
MAB4748
Carrier Free
MAB4748-SP
Carrier Free
FAB4748V-100UG
Carrier Free
FAB4748U-100UG
Carrier Free
FAB4748T-100UG
Carrier Free
FAB4748S-100UG
Carrier Free
FAB4748R-100UG
Carrier Free
FAB4748N-100UG
Carrier Free
FAB4748G-100UG
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Jagged 2 Antibody (746513) [Janelia Fluor® 646] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Jagged 2
Met27-Leu1084
Accession # Q9QYE5
Specificity
Detects mouse Jagged 2 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) Jagged 1, rhJagged 2, recombinant rat Jagged 1 is observed.
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
JAG2
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Jagged 2 Antibody (746513) [Janelia Fluor® 646]

  • HJ2
  • JAG2
  • Jagged 2
  • Jagged2
  • protein jagged-2
  • SER2

Background

The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Isotype Controls

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Notch Antibody Proves Metastatic Lung Cancer Has a Jagged Edge
We at Novus Biologicals are one of the leading antibody suppliers for cancer research. In a recent Notch antibody study, the Notch ligand Jagged 2 was found to promote the growth of metastatic lung cancer cells by inhibiting miR-200, which blocks epit...  Read full blog post.
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Bioinformatics

Gene Symbol JAG2