ITPR2 Antibody Blocking Peptide Summary
Description |
A human ITPR2 antibody blocking peptide. Source: Synthetic Amino Acid Sequence: C-PIEESNILSPVQD |
Source |
Synthetic |
Protein/Peptide Type |
Antibody Blocking Peptide |
Gene |
ITPR2 |
Purity |
>50%, by HPLC |
Applications/Dilutions
Dilutions |
|
Application Notes |
This peptide is useful as a blocking peptide for NB100-2466. For further blocking peptide related protocol, click here. |
Packaging, Storage & Formulations
Storage |
Store at -20C. Avoid freeze-thaw cycles. |
Buffer |
Lyophilized from a 5pmol/ul solution in 5% (v/v) acetonitrile/H2O and TFA salt. |
Preservative |
No Preservative |
Concentration |
LYOPH |
Purity |
>50%, by HPLC |
Reconstitution Instructions |
Reconstitute in 200ul distilled water to obtain a 0.5mg/ml peptide solution. |
Alternate Names for ITPR2 Antibody Blocking Peptide
Background
Inositol 1,4,5-triphosphate (IP3) receptors are a form of ligand-gated ion channels that are activated by cytosolic Ca2+ and IP3. They are localized to intracellular membranes, such as the endoplasmic reticulum, and mediate the mobilization of intracellular Ca2+ stores. IP3 receptors play an important role in intracellular Ca2+ signaling in a variety of cell types. There are three IP3 receptor subtypes; IP3R1, IP3R2 and IP3R3, which exist as homo- and heterotetramers. All subtypes are closely associated with calmodulin and FK506-binding protein and are modulated through phosphorylation by PKA, PKC, PKG and CaMKII.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are
guaranteed for 3 months from date of receipt.
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