Intelectin-1/Omentin Antibody (746420)

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Intelectin (endothelial lectin; also ITLN-1 and omentin) is a 34 kDa Ca-dependent galactofuranose-binding lectin that is not a C-type lectin. It is expressed in intestinal and airway epithelium and appears to participate in insulin signaling and microbe recognition. Intelectin-1 is upregulated in asthma and contributes to allergic airway inflammation. The mouse Intelectin-1 preproprecursor is 313 amino acids (aa) in length. It contains a 19 aa signal sequence, a 279 aa mature segment (aa 20-298), and a 15 aa C-terminal proregion that is cleaved to generate a GPI-linkage. Soluble Intelectin-1 can be released from omental adipose tissue and malignant pleural mesothelioma. One fibrinogen-related domain exists in the mature molecule (aa 32-251). Human Intelectin-1 exists as a disulfide-linked glycosylated homotrimer; mouse is unglycosylated and a monomer. Mature mouse Intelectin-1 is 82% aa identical to human Intelectin-1.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 3 confirmed species: Mouse, Bacteria - Helicobacter pylori, Transgenic Mouse.

We have publications tested in 2 applications: Immunohistochemistry, Western Blot.

Showing Publications 1 - 3 of 3.

Publications using MAB8074	Applications	Species
M Sigal, MDM Reinés, S Müllerke, C Fischer, M Kapalczyns, H Berger, ERM Bakker, HJ Mollenkopf, ME Rothenberg, B Wiedenmann, S Sauer, TF Meyer R-spondin-3 induces secretory, antimicrobial Lgr5+ cells in the stomach Nat. Cell Biol., 2019-06-24;21(7):812-823. 2019-06-24 [PMID: 31235935] (Immunohistochemistry, Western Blot, Bacteria - Helicobacter pylori, Mouse, Transgenic Mouse)	Immunohistochemistry, Western Blot	Bacteria - Helicobacter pylori, Mouse, Transgenic Mouse
Satomi Kagota, Kana Maruyama-Fumoto, Saki Iwata, Miho Shimari, Shiori Koyanagi, Yayoi Shiokawa et al. Perivascular Adipose Tissue-Enhanced Vasodilation in Metabolic Syndrome Rats by Apelin and N-Acetyl–l-Cysteine-Sensitive Factor(s) International Journal of Molecular Sciences 2018-12-28 [PMID: 30597883]
SS Rao, Y Hu, PL Xie, J Cao, ZX Wang, JH Liu, H Yin, J Huang, YJ Tan, J Luo, MJ Luo, SY Tang, TH Chen, LQ Yuan, EY Liao, R Xu, ZZ Liu, CY Chen, H Xie Omentin-1 prevents inflammation-induced osteoporosis by downregulating the pro-inflammatory cytokines Bone Res, 2018-03-30;6(0):9. 2018-03-30 [PMID: 29619269] (Western Blot, Mouse)	Western Blot	Mouse

Array MAB8074

• Intelectin-1/Omentin Antibodies
• Intelectin-1/Omentin ELISA Kits
• Intelectin-1/Omentin Proteins
• Intelectin-1/Omentin Proteins and Enzyme
• Intelectin-1/Omentin ELISA