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ILT6/CD85e/LILRA3 Antibody (293106)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clone
293106
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

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ILT6/CD85e/LILRA3 Antibody (293106) Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human LILRA3/CD85e
Arg18-Glu439
Accession # Q8N6C8
Specificity
Detects human LILRA3/CD85e in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) ILT1, 2, 3, 4, 5, rhLIR6, or rhLIR8 is observed.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
LILRA3
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1 ug/mL

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for ILT6/CD85e/LILRA3 Antibody (293106)

  • CD85 antigen-like family member E
  • CD85e antigen
  • CD85e
  • HM31
  • HM43
  • ILT6
  • ILT-6
  • ILT6CD85e
  • Immunoglobulin-like transcript 6
  • leucocyte immunoglobulin-like receptor
  • Leukocyte immunoglobulin-like receptor 4
  • leukocyte immunoglobulin-like receptor A3
  • leukocyte immunoglobulin-like receptor subfamily A member 3
  • leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member3
  • LILRA3
  • LIR4
  • LIR4CD85E
  • LIR-4HM43e3
  • Monocyte inhibitory receptor HM43/HM31

Background

ILT6, also known as CD85e, LIR4, and LILRA3, contains four Ig-like C2-type domains and is the only ILT family member that lacks a transmembrane and cytoplasmic domain. ILT proteins modulate immune responses through interactions with class I MHC molecules. Several polymorphisms of ILT6 have been described, and loss of ILT6 is associated with the development of multiple sclerosis. Human and chimpanzee ILT6 share 84% amino acid sequence identity. ILT6 orthologs have not been described in other species.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol LILRA3
Uniprot