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IL-20R alpha Antibody (038)

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Immunohistochemistry-Paraffin: IL-20R alpha Antibody (038) [NBP2-89469] - Staining of human IL20Ra in human skin with rabbit monoclonal antibody (1:200). Positive staining was localized to stratified squamous epithelium.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, IHC
Clone
038
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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IL-20R alpha Antibody (038) Summary

Description
This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.
Additional Information
Recombinant Monoclonal Antibody
Immunogen
This antibody was obtained from a rabbit immunized with purified, recombinant Human IL-20R alpha (Accession#: NP_055247.3; Met 1-Lys 250).
Specificity
No cross-reactivity in ELISA with:

Human IFNgR1
Human IL10RB
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
IL20RA
Purity
Protein A purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA 1:1000-1:2000
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:100-1:500

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
0.2 um filtered solution in PBS
Preservative
No Preservative
Purity
Protein A purified

Alternate Names for IL-20R alpha Antibody (038)

  • class II cytokine receptor ZCYTOR7
  • CRF2-8
  • Cytokine receptor class-II member 8
  • Cytokine receptor family 2 member 8
  • FLJ40993
  • IL-20 R alpha
  • IL20R alpha
  • IL-20R alpha
  • IL-20R1
  • IL-20R1IL-20 receptor subunit alpha
  • IL20RA
  • IL-20Ra
  • IL-20R-alpha
  • interleukin 20 receptor, alpha
  • interleukin-20 receptor I
  • interleukin-20 receptor subunit alpha
  • zcytor7

Background

Official Gene Symbol: IL20RA Gene ID: 53832 (Human) Gene Map Locus: 6q22.33-q23.1 (Human) IL20RA, is a subunit of IL20R, a member of Cytokine Class II receptor super family. It consists of a central transmembrane domain and functionally induces IL20 and IL26 signaling in epithelial cells and keratinocytes. It associates with IL-20RB and forms a functional receptor complex for IL20, IL19, and IL24. It also associates with IL-10RB and forms a unique heterodimeric functional receptor complex for IL-26. Upon ligand binding, it induces signaling through activation of STAT3 and STAT1. IL20RA is specifically expressed in skin suggesting a prominent role in growth and proliferation of keratinocytes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol IL20RA