Human VEGF-D DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Vascular endothelial growth factor D (VEGF-D) is a homodimeric ligand of VEGF R3/Flt-4 and is synthesized with N- and C-terminal propeptides. Fully processed VEGF-D containing only the VEGF homology domain can additionally bind and activate VEGF R2/KDR/Flk-1. VEGF-D is expressed in adult lung, heart, muscle, and small intestine, and is most abundantly expressed in fetal lungs and skin. VEGF R3 is strongly expressed in lymphatic endothelial cells and is essential for regulation of the growth and differentiation of lymphatic endothelium. While VEGF-C is the critical ligand for VEGF R3 during embryonic lymphatic development, while VEGF-D is most active in neonatal lymphatic maturation and bone growth.

We have publications tested in 1 confirmed species: Human.

Showing Publications 1 - 5 of 5.

Publications using DY622	Applications	Species
S Kuriyama, T Yamada, A Matsuda, G Takahashi, T Iwai, K Takeda, K Ueda, T Miyasaka, Y Yokoyama, S Shinji, H Sonoda, R Ohta, K Yonaga, S Kanaka, H Yoshida Biomarkers for anti-vascular endothelial growth factor drugs Oncology Letters, 2022-11-07;24(6):463. 2022-11-07 [PMID: 36406183] (Human)		Human
G Varricchi, S Loffredo, L Bencivenga, AL Ferrara, G Gambino, N Ferrara, A de Paulis, G Marone, G Rengo Angiopoietins, Vascular Endothelial Growth Factors and Secretory Phospholipase A2 in Ischemic and Non-Ischemic Heart Failure J Clin Med, 2020-06-19;9(6):. 2020-06-19 [PMID: 32575548] (Human)		Human
Débora C Bastos Effects of fatty acid synthase inhibitors on lymphatic vessels: an in vitro and in vivo study in a melanoma model Lab. Invest, 2016-12-05;0(0):. 2016-12-05 [PMID: 27918556] (Human)		Human
Lash GE, Naruse K, Innes BA, Robson SC, Searle RF, Bulmer JN Secretion of angiogenic growth factors by villous cytotrophoblast and extravillous trophoblast in early human pregnancy. Placenta, 2010-03-24;31(6):545-8. 2010-03-24 [PMID: 20338637] (Human)		Human
Akahane M, Akahane T, Matheny SL, Shah A, Okajima E, Thorgeirsson UP Vascular endothelial growth factor-D is a survival factor for human breast carcinoma cells. Int. J. Cancer, 2006-02-15;118(4):841-9. 2006-02-15 [PMID: 16152591] (Human)		Human

Array DY622

• VEGF-D Antibodies
• VEGF-D ELISA Kits
• VEGF-D Lysate
• VEGF-D Protein
• VEGF-D ELISAs
• VEGF-D Proteins and Enzymes