Human TRAIL/TNFSF10 Quantikine ELISA Kit

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

TNF-related apoptosis-inducing ligand (TRAIL), also known as Apo-2 ligand and TNFSF10, is a type II transmembrane protein with a carboxy-terminal extracellular domain that exhibits homology to other TNF superfamily members. Among TNF superfamily members, TRAIL is the most homologous to Fas Ligand, sharing 28% amino acid sequence identity in their extracellular domains. Human TRAIL shares 65% amino acid sequence identity with mouse TRAIL and is active on mouse cells.

We have publications tested in 3 confirmed species: Human, Mouse, Humanized Mouse.

Showing Publications 1 - 10 of 36. Show All 36 Publications. Collapse Publications.

Publications using DTRL00	Applications	Species
N Kuehnle, SM Osborne, Z Liang, M Manzano, E Gottwein CRISPR screens identify novel regulators of cFLIP dependency and ligand-independent, TRAIL-R1-mediated cell death Cell Death and Differentiation, 2023-02-18;0(0):. 2023-02-18 [PMID: 36801923] (Human)		Human
S Ravichandr, G Grubbs, J Tang, Y Lee, C Huang, H Golding, S Khurana Systemic and mucosal immune profiling in asymptomatic and symptomatic SARS-CoV-2-infected individuals reveal unlinked immune signatures Science Advances, 2021-10-13;7(42):eabi6533. 2021-10-13 [PMID: 34644111] (Human)		Human
MC Kuo, WA Chang, LY Wu, YC Tsai, YL Hsu Hypoxia-Induced Epithelial-to-Mesenchymal Transition in Proximal Tubular Epithelial Cells through miR-545-3p-TNFSF10 Biomolecules, 2021-07-15;11(7):. 2021-07-15 [PMID: 34356656] (Human)		Human
E Hadad, S Rudnick-Gl, E Itzhaki, MY Avivi, I Grinberg, Y Elias, S Margel Engineering of Doxorubicin-Encapsulating and TRAIL-Conjugated Poly(RGD) Proteinoid Nanocapsules for Drug Delivery Applications Polymers, 2020-12-16;12(12):. 2020-12-16 [PMID: 33339090] (Human)		Human
YW Eom, R Akter, W Li, S Lee, S Hwang, J Kim, MY Cho M1 Macrophages Promote TRAIL Expression in Adipose Tissue-Derived Stem Cells, Which Suppresses Colitis-Associated Colon Cancer by Increasing Apoptosis of CD133+ Cancer Stem Cells and Decreasing M2 Macrophage Population Int J Mol Sci, 2020-05-29;21(11):. 2020-05-29 [PMID: 32485960] (Human)		Human
L Cheng, H Yu, JA Wrobel, G Li, P Liu, Z Hu, XN Xu, L Su Identification of pathogenic TRAIL-expressing innate immune cells during HIV-1 infection in humanized mice by scRNA-Seq JCI Insight, 2020-06-04;5(11):. 2020-06-04 [PMID: 32406872] (Humanized Mouse)		Humanized Mouse
A Masuda, Y Isobe, K Sugimoto, M Yoshimori, A Arai, N Komatsu Efficient recruitment of c-FLIPL to the death-inducing signaling complex leads to Fas resistance in natural killer-cell lymphoma Cancer Sci., 2020-01-31;111(3):807-816. 2020-01-31 [PMID: 31908105] (Human)		Human
EJ Schenck, KC Ma, DR Price, T Nicholson, C Oromendia, ER Gentzler, E Sanchez, RM Baron, LE Fredenburg, JW Huh, II Siempos, AM Choi Circulating cell death biomarker TRAIL is associated with increased organ dysfunction in sepsis JCI Insight, 2019-05-02;4(9):. 2019-05-02 [PMID: 31045578] (Human)		Human
F Rossignoli, C Spano, G Grisendi, EM Foppiani, G Golinelli, I Mastrolia, M Bestagno, O Candini, T Petrachi, A Recchia, F Miselli, G Rovesti, G Orsi, E Veronesi, G Medici, B Petocchi, M Pinelli, EM Horwitz, P Conte, M Dominici MSC-Delivered Soluble TRAIL and Paclitaxel as Novel Combinatory Treatment for Pancreatic Adenocarcinoma Theranostics, 2019-01-01;9(2):436-448. 2019-01-01 [PMID: 30809285] (Human)		Human
C Spano, G Grisendi, G Golinelli, F Rossignoli, M Prapa, M Bestagno, O Candini, T Petrachi, A Recchia, F Miselli, G Rovesti, G Orsi, A Maiorana, P Manni, E Veronesi, MS Piccinno, A Murgia, M Pinelli, EM Horwitz, S Cascinu, P Conte, M Dominici Soluble TRAIL Armed Human MSC As Gene Therapy For Pancreatic Cancer Sci Rep, 2019-02-11;9(1):1788. 2019-02-11 [PMID: 30742129] (Human)		Human
MV Arcidiacon, E Rimondi, E Maietti, E Melloni, V Tisato, S Gallo, JM Valdiviels, E Fernández, À Betriu, R Voltan, G Zauli, S Volpato, P Secchiero Relationship between low levels of circulating TRAIL and atheromatosis progression in patients with chronic kidney disease PLoS ONE, 2018-09-11;13(9):e0203716. 2018-09-11 [PMID: 30204795] (Human)		Human
V Tisato, S Gallo, E Melloni, C Celeghini, A Passaro, G Zauli, P Secchiero, C Bergamini, A Trentini, G Bonaccorsi, G Valacchi, G Zuliani, C Cervellati TRAIL and Ceruloplasmin Inverse Correlation as a Representative Crosstalk between Inflammation and Oxidative Stress Mediators Inflamm., 2018-07-26;2018(0):9629537. 2018-07-26 [PMID: 30147446] (Human)		Human
J Yang, FR LeBlanc, SA Dighe, CE Hamele, TL Olson, DJ Feith, TP Loughran TRAIL mediates and sustains constitutive NF-κB activation in LGL leukemia Blood, 2018-04-26;0(0):. 2018-04-26 [PMID: 29699990] (Human)		Human
D Morano, A Rolfo, V Tisato, A Farina, E Rimondi, G Scutiero, P Greco, G Bonaccorsi, T Todros Lower maternal serum tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) levels in early preeclampsia. A retrospective study Pregnancy Hypertens, 2018-02-07;12(0):1-5. 2018-02-07 [PMID: 29674187] (Human)		Human
J Wagner, CL Kline, L Zhou, V Khazak, WS El-Deiry Anti-tumor effects of ONC201 in combination with VEGF-inhibitors significantly impacts colorectal cancer growth and survival in vivo through complementary non-overlapping mechanisms J. Exp. Clin. Cancer Res., 2018-01-22;37(1):11. 2018-01-22 [PMID: 29357916] (Mouse)		Mouse
Roybal K, Williams J, Morsut L, Rupp L, Kolinko I, Choe J, Walker W, McNally K, Lim W Engineering T Cells with Customized Therapeutic Response Programs Using Synthetic Notch Receptors. Cell, 2016-09-29;167(2):419-432.e16. 2016-09-29 [PMID: 27693353] (Human)		Human
Expression of osteoprotegerin and its ligands, RANKL and TRAIL, in rheumatoid arthritis Sci Rep, 2016-07-12;6(0):29713. 2016-07-12 [PMID: 27403809] (Human)		Human
Clonal evolution in patients with chronic lymphocytic leukaemia developing resistance to BTK inhibition Nat Commun, 2016-05-20;7(0):11589. 2016-05-20 [PMID: 27199251] (Human)		Human
Mohr A, Yu R, Zwacka R TRAIL-receptor preferences in pancreatic cancer cells revisited: Both TRAIL-R1 and TRAIL-R2 have a licence to kill. BMC Cancer, 2015-07-03;15(0):494. 2015-07-03 [PMID: 26138346] (Human)		Human
Zhou C, Long Y, Yang H, Zhu C, Ma Q, Zhang Y TRAIL Is Decreased Before 20 Weeks Gestation in Women with Hypertensive Disorders of Pregnancy. PLoS ONE, 2015-06-01;10(6):e0128425. 2015-06-01 [PMID: 26030414] (Human)		Human
Choi S, Lee Y, Kwak P, Lee J, Kim S, Lee S, Phi J, Wang K, Song J, Song S, Joo K, Kim S Clinically applicable human adipose tissue-derived mesenchymal stem cells delivering therapeutic genes to brainstem gliomas. Cancer Gene Ther, 2015-05-29;22(6):302-11. 2015-05-29 [PMID: 26021486] (Human)		Human
Kang S, Kang D, Bakhtiar Ul Islam S, Je S, Kim J, Song J Silencing Daxx increases the anti-tumor activity of a TRAIL/shRNA Bcl-xL-expressing oncolytic adenovirus through enhanced viral replication and cellular arrest. Cell Signal, 2015-03-05;27(6):1214-24. 2015-03-05 [PMID: 25748050] (Human)		Human
Teng J, Hejazi S, Badr C, Tannous B Systemic anticancer neural stem cells in combination with a cardiac glycoside for glioblastoma therapy. Stem Cells, 2014-08-01;32(8):2021-32. 2014-08-01 [PMID: 24801379] (Human, Mouse)		Human, Mouse
Ray A, Tian Z, Das D, Coffman R, Richardson P, Chauhan D, Anderson K A novel TLR-9 agonist C792 inhibits plasmacytoid dendritic cell-induced myeloma cell growth and enhance cytotoxicity of bortezomib. Leukemia, 2014-01-30;28(8):1716-24. 2014-01-30 [PMID: 24476765] (Human)		Human
Zhang Y, Patel B, Dey A, Ghorani E, Rai L, Elham M, Castleton AZ, Fielding AK Attenuated, oncolytic, but not wild-type measles virus infection has pleiotropic effects on human neutrophil function. J. Immunol., 2011-12-16;188(3):1002-10. 2011-12-16 [PMID: 22180616] (Human)		Human
Bem RA, Bos AP, Wosten-van Asperen RM, Bruijn M, Lutter R, Sprick MR, van Woensel JB Potential role of soluble TRAIL in epithelial injury in children with severe RSV infection. Am. J. Respir. Cell Mol. Biol., 2009-07-27;42(6):697-705. 2009-07-27 [PMID: 19635930] (Human)		Human
Niessner A, Hohensinner PJ, Rychli K, Neuhold S, Zorn G, Richter B, Hulsmann M, Berger R, Mortl D, Huber K, Wojta J, Pacher R Prognostic value of apoptosis markers in advanced heart failure patients. Eur. Heart J., 2009-02-04;30(7):789-96. 2009-02-04 [PMID: 19196721] (Human)		Human
Secchiero P, Lamberti G, Corallini F, Melloni E, Guarnotta C, Sebastiani A, Zauli G Conjunctival sac fluid contains elevated levels of soluble TRAIL: implications for the anti-tumoral surveillance of the anterior surface of the eye. J. Cell. Physiol., 2009-01-01;218(1):199-204. 2009-01-01 [PMID: 18780288] (Human)		Human
Secchiero P, Melloni E, Corallini F, Beltrami AP, Alviano F, Milani D, D'Aurizio F, di Iasio MG, Cesselli D, Bagnara GP, Zauli G Tumor necrosis factor-related apoptosis-inducing ligand promotes migration of human bone marrow multipotent stromal cells. Stem Cells, 2008-09-04;26(11):2955-63. 2008-09-04 [PMID: 18772312] (Human)		Human
Chamoux E, Houde N, L'Eriger K, Roux S Osteoprotegerin decreases human osteoclast apoptosis by inhibiting the TRAIL pathway. J. Cell. Physiol., 2008-08-01;216(2):536-42. 2008-08-01 [PMID: 18338379] (Human)		Human
Hoffmann O, Priller J, Prozorovski T, Schulze-Topphoff U, Baeva N, Lunemann JD, Aktas O, Mahrhofer C, Stricker S, Zipp F, Weber JR TRAIL limits excessive host immune responses in bacterial meningitis. J. Clin. Invest., 2007-07-01;117(7):2004-13. 2007-07-01 [PMID: 17571163] (Human)		Human
Corallini F, Celeghini C, Rizzardi C, Pandolfi A, Di Silvestre S, Vaccarezza M, Zauli G Insulin down-regulates TRAIL expression in vascular smooth muscle cells both in vivo and in vitro. J. Cell. Physiol., 2007-07-01;212(1):89-95. 2007-07-01 [PMID: 17352408] (Human)		Human
Masci P, Olencki T, Wood L, Rybicki L, Jacobs B, Williams B, Faber P, Bukowski R, Tong K, Borden EC Gene modulatory effects, pharmacokinetics, and clinical tolerance of interferon-alpha1b: a second member of the interferon-alpha family. Clin. Pharmacol. Ther., 2007-03-01;81(3):354-61. 2007-03-01 [PMID: 17339865] (Human)		Human
Claessens YE, Fontenay M, Pene F, Chiche JD, Guesnu M, Hababou C, Casadevall N, Dhainaut JF, Mira JP, Cariou A Erythropoiesis abnormalities contribute to early-onset anemia in patients with septic shock. Am. J. Respir. Crit. Care Med., 2006-03-30;174(1):51-7. 2006-03-30 [PMID: 16574939] (Human)		Human
Gibellini D, Vitone F, Schiavone P, Re MC HIV-1 tat protein and cell proliferation and survival: a brief review. New Microbiol., 2005-04-01;28(2):95-109. 2005-04-01 [PMID: 16035254] (Human)		Human
Campioni D, Secchiero P, Corallini F, Melloni E, Capitani S, Lanza F, Zauli G Evidence for a role of TNF-related apoptosis-inducing ligand (TRAIL) in the anemia of myelodysplastic syndromes. Am. J. Pathol., 2005-02-01;166(2):557-63. 2005-02-01 [PMID: 15681838] (Human)		Human
Show All 36 Publications. Collapse Publications.

Array DTRL00

• TRAIL/TNFSF10 Antibodies
• TRAIL/TNFSF10 Antibody Pair
• TRAIL/TNFSF10 ELISA Kits
• TRAIL/TNFSF10 Lysate
• TRAIL/TNFSF10 Proteins
• TRAIL/TNFSF10 Proteins and Enzymes
• TRAIL/TNFSF10 ELISAs