Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Human Granzyme A DuoSet ELISA, 5 Plate
CTL Tryptase
CTLA3
CTLA3Granzyme A (Cytotoxic T-lymphocyte-associated serine esterase-3; Hanukah factorserine protease)
Cytotoxic T-lymphocyte proteinase 1
EC 3.4.21
Fragmentin-1
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
Granzyme A
Granzyme-1
GZMA
H factor
Hanukkah factor
HF
HFSP
HFSPEC 3.4.21.78
Background
Granzyme family serine proteases are stored in the granules of cytotoxic T lymphocytes and natural killer cells. Granzymes contain one S1 protease domain and are synthesized as preproproteins. Granzymes are released toward pathogen infected or transformed target cells during cellular immune reactions. Target cell entry by granzymes is through perforin channels. Granzymes trigger apoptosis by caspase-dependent and -independent mechanisms. There are five granzymes (A, B, G, H and K) in human and many more in mouse and rat.