This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Immunogen
Human HLA Class II (DP, DQ, DR)
Specificity
Recognizes HLA Class II beta chains of human major histocompatability antigen, Mw 28 kD. It reacts with a monomorphic determinant common to each beta chain type. The antigen is expressed by human B lymphocytes, monocytes and activated T lymphocytes.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
HLA-DQA1
Purity
Protein G purified
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Alternate Names for HLA DQ/DR/DP Antibody (WR18) [Biotin]
CD
CELIAC1DQ alpha 1 chain
DC-1 alpha chain
DQ-A1
FLJ27088
FLJ27328
GSE
HLA class II histocompatibility antigen, DQ(W3) alpha chain
HLA-DCA
HLA-DQA
leucocyte antigen DQA1
leukocyte antigen alpha chain
major histocompatibility complex, class II, DQ alpha 1
MGC149527
MHC class II antigen
MHC class II DQA1
MHC class II HLA-D alpha glycoprotein
MHC class II HLA-DQ-alpha-1
MHC class II surface glycoprotein
MHC HLA-DQ alpha
Background
The major histocompatibility complex (MHC) is a large genomic region or gene family found in most vertebrates containing many genes with important immune system roles. In humans, the MHC spans almost 4 megabases of chromosome 6 and includes more than 200 known genes, of which about half have known immmunological functions. The best known genes in the MHC region are the subset that encodes cell-surface antigen-presenting proteins. In humans, these genes are referred to as human leukocyte antigen (HLA) genes. The most intensely studied HLA genes are: HLA A, HLA B, HLA C, HLA DPA, HLA DPB1, HLA DQA1, HLA DQB1, HLA DRA, and HLA DRB1. In humans, the HLA is divided into three regions: Class I, II, and III. The A, B, and C genes belong to HLA class I while the six D genes belong to class II.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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