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GRF2 Antibody

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Independent Antibodies: Western Blot: GRF2 Antibody [NBP1-06501] - Whole cell lysate from HeLa cells. C3G was also immunoprecipitated by rabbit anti-C3G antibody NBP1-06500.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.2 mg/ml
Validated by:
 

Independent Antibodies

       

Order Details

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GRF2 Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 375 and 425 of human CRK SH3-binding GNRP using the numbering given in entry NP_005303.2 (GeneID 2889).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
RAPGEF1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunoprecipitation 1:10-1:500
  • Western Blot 1:2000-1:10000
Control
GRF2 Overexpression Lysate

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for GRF2 Antibody

  • C3GGRF2guanine nucleotide-releasing factor 2 (specific for crk proto-oncogene)
  • CRK SH3-binding GNRP
  • DKFZp781P1719
  • Guanine nucleotide-releasing factor 2
  • Protein C3G
  • Rap guanine nucleotide exchange factor (GEF) 1
  • rap guanine nucleotide exchange factor 1

Background

This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for GRF2 Antibody (NBP1-06501) (0)

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for GRF2 Antibody (NBP1-06501) (0)

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol RAPGEF1
Entrez
Uniprot