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Glucosylceramidase/GBA Antibody

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Western Blot: Glucosylceramidase/GBA Antibody [H00002629-B01P] - Analysis of GBA expression in U-2 OS.
Western Blot: Glucosylceramidase/GBA Antibody [H00002629-B01P] - Analysis of GBA expression in transfected 293T cell line by GBA polyclonal antibody. Lane 1: GBA transfected lysate(58.96 KDa). Lane 2: Non-transfected ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Mouse
Conjugate
Unconjugated

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Glucosylceramidase/GBA Antibody Summary

Description
Quality control test: Antibody reactive against mammalian transfected lysate.
Immunogen
GBA (AAH03356.1, 1 a.a. - 536 a.a.) full-length human protein. MEFSSPSREECPKPLSRVSIMAGSLTGLLLLQAVSWASGARPCIPKSFGYSSVVCVCNATYCDSFDPPTFPALGTFSRYESTRSGRRMELSMGPIQANHTGTGLLLTLQPEQKFQKVKGFGGAMTDAAALNILALSPPAQNLLLKSYFSEEGIGYNIIRVPMASCDFSIRTYTYADTPDDFQLHNFSLPEEDTKLKIPLIHRALQLAQRPVSLLASPWTSPTWLKTNGAVNGKGSLKGQPGDIYHQTWARYFVKFLDAYAEHKLQFWAVTAENEPSAGLLSGYPFQCLGFTPEHQRDFIARDLGPTLANSTHHNVRLLMLDDQRLLLPHWAKVVLTDPEAAKYVHGIAVHWYLDFLAPAKATLGETHRLFPNTMLFASEACVGSKFWEQSVRLGSWDRGMQYSHSIITNLLYHVVGWTDWNLALNPEGGPNWVRNFVDSPIIVDITKDTFYKQPMFYHLGHFSKFIPEGSQRVGLVASQKNDLDAVALMHPDGSAVVVVLNRSSKDVPLTIKDPAVGFLETISPGYSIHTYLWRRQ
Specificity
GBA - glucosidase, beta; acid (includes glucosylceramidase),
Isotype
IgG
Clonality
Polyclonal
Host
Mouse
Gene
GBA1
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Antibody reactivity against Recombinant Protein with GST tag by WB and also on transfected lysate in WB. GST tag alone is used as a negative control. IP usage reported by a customer review.
Reviewed Applications
Read 1 Review rated 5
using
H00002629-B01P in the following application:

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Glucosylceramidase/GBA Antibody

  • Acid beta-glucosidase
  • Alglucerase
  • beta-glucocerebrosidase
  • D-glucosyl-N-acylsphingosine glucohydrolase
  • EC 3.2.1.45
  • GBA
  • GBA1
  • GC
  • GCB
  • GLUC
  • glucosidase, beta, acid
  • glucosidase, beta; acid (includes glucosylceramidase)
  • Glucosylceramidase
  • Imiglucerase
  • lysosomal glucocerebrosidase

Background

This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Glucosylceramidase/GBA Antibody (H00002629-B01P) (0)

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Review for Glucosylceramidase/GBA Antibody (H00002629-B01P) (1) 51

Average Rating: 5
(Based on 1 review)
We have 1 review tested in 1 species: Human.

Reviews using H00002629-B01P:
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Images Ratings Applications Species Date Details
  5
reviewed by:
Verified Customer
IP Human 05/10/2010
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Summary

ApplicationImmunoprecipitation
Sample TestedCell lysate
SpeciesHuman

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Secondary Antibodies

 

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Verified Customer
05/10/2010
Application: IP
Species: Human

Bioinformatics

Gene Symbol GBA1
Entrez
Uniprot