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GLP1 Antibody (4) [mFluor Violet 610 SE]

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Product Details

Summary
Reactivity Hu, Mu, MaSpecies Glossary
Applications ELISA, IHC
Clone
4
Clonality
Monoclonal
Host
Mouse
Conjugate
mFluor Violet 610 SE

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GLP1 Antibody (4) [mFluor Violet 610 SE] Summary

Immunogen
Synthetic GLP-1(7-17)
Epitope
Free N-terminus of GLP-1(7-37) and GLP-1(7-36)amide.
Specificity
This antibody binds the free N-terminus of GLP-1(7-37) and GLP-1(7-36)amide and shows <0.2% cross-reactivity with GLP-1(1-37), GLP-1(9-36)amide, human GIP and exendin-4. Cross-reacts approximately 1% with human GLP-2.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
GCG
Purity
Protein A or G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for GLP1 Antibody (4) [mFluor Violet 610 SE]

  • glicentin-related polypeptide
  • GLP1
  • GLP-1
  • glucagon-like peptide 1
  • GRPP

Background

Glucagon-like peptide-1 (GLP-1) is an incretin hormone secreted from enteroendocrine L cells in response to ingested nutrients. The closely related peptides glucagon-like peptide (GLP-1) and glucagon have opposing effects on blood glucose. GLP-1 induces glucose-dependent insulin secretion in the pancreas, while glucagon stimulates gluconeogenesis and glycogenolysis in the liver. Glucagon is processed from a large precursor, proglucagon, in a tissue-specific manner in pancreatic alpha-cells. The identification of a hybrid peptide acting as both a GLP-1 agonist and a glucagon antagonist would provide a novel approach for the treatment of type 2 diabetes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Array NBP2-23558MFV610

Research Areas for GLP1 Antibody (NBP2-23558MFV610)

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mFluor Violet Conjugated Antibodies

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Bioinformatics

Gene Symbol GCG