GATA-4 Antibody (532020) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

GATA-4 belongs to the GATA family of transcription factors, which bind to the consensus DNA sequence (A/T) GATA (A/G) to control diverse tissue-specific programs of gene expression and morphogenesis. It is widely expressed in mesodermal- and endodermal-derived tissues. GATA-4 interacts with other transcription factors such as NKX2.5, and myocyte enhancer factor 2 to regulate cardiac myocyte-specific gene expression. GATA-4 contains 2 zinc finger-binding domains and migrates at 56 kDa in SDS-PAGE gels. Human GATA-4 share 93%, 93% and 92% amino acid sequence identity with porcine, rat and mouse GATA-4, respectively.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 3 applications: ICC, IHC-Fr, Western Blot.

Showing Publications 1 - 7 of 7.

Publications using MAB2606	Applications	Species
Victoria Heredia-Soto, Laura Gutiérrez-Sainz, Ismael Ghanem, Laura Guerra, Elena Palacios, Marta de Uribe et al. The Relationship between the Expression of GATA4 and GATA6 with the Clinical Characteristics and Prognosis of Resectable Pancreatic Adenocarcinoma Biomedicines 1/18/2023 [PMID: 36830789]
Yoshiki Nakashima, Chika Miyagi-Shiohira, Issei Saitoh, Masami Watanabe, Masayuki Matsushita, Masayoshi Tsukahara et al. Induced hepatic stem cells are suitable for human hepatocyte production iScience 10/21/2022 [PMID: 36147945]
N Arroyo, L Villamayor, I Díaz, R Carmona, M Ramos-Rodr, R Muñoz-Chap, L Pasquali, MG Toscano, F Martin, DA Cano, A Rojas GATA4 induces liver fibrosis regression by deactivating hepatic stellate cells JCI Insight, 2021-12-08;0(0):. 2021-12-08 [PMID: 34699385] (Western Blot, Mouse)	Western Blot	Mouse
Collins D, Hapke J, Aravalli R, Steer C In vitro Differentiation of TERT-Transfected Multi-Lineage Progenitor Cells (MLPC) into Immortalized Hepatocyte-Like Cells HMER 6/1/2020 [PMID: 32607015]
Rajagopal N Aravalli, Daniel P Collins, Joel H Hapke, Andrew T Crane, Clifford J Steer <p>Hepatic Differentiation of Marmoset Embryonic Stem Cells and Functional Characterization of ESC-Derived Hepatocyte-Like Cells</p> Hepatic Medicine: Evidence and Research 2/13/2020 [PMID: 32104112]
Tea Soini, Katja Eloranta, Marjut Pihlajoki, Antti Kyrönlahti, Oyediran Akinrinade, Noora Andersson et al. Transcription factor GATA4 associates with mesenchymal-like gene expression in human hepatoblastoma cells Tumour Biol 8/4/2018 [PMID: 30074440]
A Llucià-Val, C Soler-Boti, C Gálvez-Mon, S Roura, C Prat-Vidal, I Perea-Gil, B Sanchez, R Bragos, G Vunjak-Nov, A Bayes-Geni Electromechanical Conditioning of Adult Progenitor Cells Improves Recovery of Cardiac Function After Myocardial Infarction Stem Cells Transl Med, 2016-09-29;6(3):970-981. 2016-09-29 [PMID: 28297585] (ICC, IHC-Fr, Mouse)	ICC, IHC-Fr	Mouse

Array MAB2606

• GATA-4 Antibodies
• GATA-4 ELISA Kits
• GATA-4 Lysate
• GATA-4 Proteins