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GALNT12 Antibody

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Immunohistochemistry-Paraffin: GALNT12 Antibody [NBP2-14035] - Staining of human fallopian tube shows low expression as expected.
Immunohistochemistry-Paraffin: GALNT12 Antibody [NBP2-14035] - Staining of human epididymis shows high expression.
Orthogonal Strategies: Immunohistochemistry-Paraffin: GALNT12 Antibody [NBP2-14035] - Staining in human epididymis and fallopian tube tissues using anti-GALNT12 antibody. Corresponding GALNT12 RNA-seq data are ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

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GALNT12 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to the amino acids: PEGCIAVEAGMDTLIMHLCEETAPENQKFILQEDGSLFHEQSKKCVQAARKESSDSFVPLLRDCTNSDHQK
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GALNT12
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
GALNT12 Protein (NBP2-14035PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for GALNT12 Antibody

  • colorectal cancer, susceptibility to 1
  • CRCS1
  • EC 2.4.1.41
  • FLJ21212
  • GalNAc-T12
  • GALNT12
  • Polypeptide GalNAc transferase 12
  • polypeptide N-acetylgalactosaminyltransferase 12
  • Pp-GaNTase 12
  • Protein-UDP acetylgalactosaminyltransferase 12
  • UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase
  • UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 12
  • UDP-N-acetyl-alpha-D-galactosamine:polypeptideN-acetylgalactosaminyltransferase 12 (GalNAc-T12)

Background

GALNT12, also known as Polypeptide N-acetylgalactosaminyltransferase 12, has a 581 amino acid long isoform that is 67 kDa and a short 272 amino acid isoform that is 32 kDa, plays role in catalyzing the initial reaction in O-linked oligosaccharide biosynthesis, and the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor; displays activity toward non-glycosylated peptides such as Muc5AC, Muc1a and EA2, Gal-NAc-Muc5AC glycopeptide; and initializes mucin-type oligosaccharide biosynthesis in digestive organs. Studies on this protein have shown a relationship with the following disorders and diseases: colorectal cancer, colon cancer, cerebritis, thyroiditis, and prostatitis. This protein has also been shown to have interactions with MUC7, MUC1, MUC2, MUC5AC, and C1GALT1 in the pathways such as the O-linked glycosylation of mucins, metabolism of proteins, post-translational protein modification, and mucin type O-Glycan biosynthesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol GALNT12