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GABA-A R beta 3 Antibody (N87/25) [DyLight 550]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ICC/IF, IHC, MA
Clone
N87/25
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 550

GABA-A R beta 3 Antibody (N87/25) [DyLight 550] Summary

Immunogen
Fusion protein amino acids 370-433 of mouse GABA-A-R-Beta 3
Localization
Cell Membrane , Cell Junction , Synapse , Postsynaptic Cell Membrane
Specificity
Detects approx 55kDa. No cross-reactivity against GABA-A-R-Beta 2 or -Beta1.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
GABRB3
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Microarray
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Alternate Names for GABA-A R beta 3 Antibody (N87/25) [DyLight 550]

  • ECA5
  • GABA A R beta 3
  • GABA(A) receptor beta-3 subunit
  • GABA(A) receptor subunit beta-3
  • GABAA receptor beta-3 subunit
  • GABA-alpha receptor beta-2 subunit
  • GABAAR beta 3
  • GABAARb3
  • GABRB3
  • gamma-aminobutyric acid (GABA) A receptor, beta 3
  • gamma-aminobutyric acid receptor subunit beta-3
  • MGC9051

Background

The GABRB3 gene encodes a member of the ligand-gated ionic channel family. The encoded protein, GABA A Receptor beta 3, is one of at least 13 distinct subunits of a multisubunit chloride channel that serves as the receptor for gamma-aminobutyric acid, the major inhibitory transmitter of the nervous system. GABRB3 is located on the long arm of chromosome 15 in a cluster with two genes encoding related subunits of the family. Mutations in the GABA A Receptor beta 3 gene may be associated with the pathogenesis of Angelman syndrome, Prader-Willi syndrome, and autism.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for GABA-A R beta 3 Antibody (NBP1-47613R) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol GABRB3
Entrez
Uniprot