GABA-A R beta 3 Antibody (N87/25) [DyLight 550] Summary
Immunogen |
Fusion protein amino acids 370-433 of mouse GABA-A-R-Beta 3 |
Localization |
Cell Membrane , Cell Junction , Synapse , Postsynaptic Cell Membrane |
Specificity |
Detects approx 55kDa. No cross-reactivity against GABA-A-R-Beta 2 or -Beta1. |
Isotype |
IgG1 |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
GABRB3 |
Purity |
Protein G purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunocytochemistry/ Immunofluorescence
- Immunohistochemistry
- Microarray
- Western Blot
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
50mM Sodium Borate |
Preservative |
0.05% Sodium Azide |
Purity |
Protein G purified |
Alternate Names for GABA-A R beta 3 Antibody (N87/25) [DyLight 550]
Background
The GABRB3 gene encodes a member of the ligand-gated ionic channel family. The encoded protein, GABA A Receptor beta 3, is one of at least 13 distinct subunits of a multisubunit chloride channel that serves as the receptor for gamma-aminobutyric acid, the major inhibitory transmitter of the nervous system. GABRB3 is located on the long arm of chromosome 15 in a cluster with two genes encoding related subunits of the family. Mutations in the GABA A Receptor beta 3 gene may be associated with the pathogenesis of Angelman syndrome, Prader-Willi syndrome, and autism.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Secondary Antibodies
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