FoxP1 Antibody (JC12) - BSA Free

FOXP1 is a member of the Forkhead Box Protein family. These proteins are transcription factors that are characterised by a highly conserved forkhead DNA-binding domain. FOXP1 is a repressor of transcription. It forms homodimers, and also heterodimerises with FOXP2 and FOXP4, to facilitate its binding to DNA for transcriptional regulation. A chromosomal aberration involving FOXP1 is found in acute lymphoblastic leukaemia, and FOXP1 is also implicated in mental retardation with language impairment and autistic features (MRLIAF). Chromosomal translocation of FOXP1 is implicated in mucosa-associated lymphoid tissue (MALT) lymphoma.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 5 applications: ICC/IF, IF/IHC, IHC-P, IP, WB.

Showing Publications 1 - 8 of 8.

Publications using NB100-65125	Applications	Species
Gars E, Butzmann A, Ohgami R et al. The life and death of the germinal center Ann Diagn Pathol 2019-11-13 [PMID: 31751845] (IF/IHC, Human)	IF/IHC	Human
Xie Y, Bulbul MA, Ji L et al. p53 Expression Is a Strong Marker of Inferior Survival in De Novo Diffuse Large B-Cell Lymphoma and May Have Enhanced Negative Effect With MYC Coexpression: A Single Institutional Clinicopathologic Study. Am. J. Clin. Pathol. 2014-04-01 [PMID: 24619762] (IHC-P, Human)	IHC-P	Human
Brown PJ, Ashe SL, Leich E et al. Potentially oncogenic B-cell activation-induced smaller isoforms of FOXP1 are highly expressed in the activated B cell-like subtype of DLBCL. Blood. 2008-03-01 [PMID: 18077790] (WB, IF/IHC, Human)	WB, IF/IHC	Human
Li B, Samanta A, Song X et al. FOXP3 is a homo-oligomer and a component of a supramolecular regulatory complex disabled in the human XLAAD/IPEX autoimmune disease. Int Immunol. 2007-07-01 [PMID: 17586580] (IP, Human)	IP	Human
Loddenkemper C, Maul J, Berg E et al. Analysis of FOXP3 protein expression in human CD4(+)CD25(+) regulatory T cells at the single-cell level. Eur J Immunol. 2006-01-01 [PMID: 16380960] (IF/IHC, Human)	IF/IHC	Human
Banham, AH et al. Expression of the FOXP1 transcription factor is strongly associated with inferior survival in patients with diffuse large B-cell lymphoma. Clin Cancer Res11:1065 - 1072. 2005-01-01 [PMID: 15709173]
Fox SB, Brown P, Han C et al. Expression of the forkhead transcription factor FOXP1 is associated with estrogen receptor alpha and improved survival in primary human breast carcinomas. Clin Cancer Res. 2004-05-15 [PMID: 15161711] (IF/IHC, WB, ICC/IF, Human)	IF/IHC, WB, ICC/IF	Human
Banham, AH et al. The FOXP1 winged helix transcription factor is a novel candidate tumor suppressor gene on chromosome 3p. Cancer Res 61:8820 - 8829. 2001-01-01 [PMID: 11751404]

Array NB100-65125

• FoxP1 Antibodies
• FoxP1 Lysate
• FoxP1 Proteins