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Flt-3/Flk-2/CD135 Antibody (66903) [mFluor Violet 450 SE]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
66903
Clonality
Monoclonal
Host
Mouse
Conjugate
mFluor Violet 450 SE

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB812U-100UG
Alexa Fluor 405
FAB812V-100UG
Alexa Fluor 488
FAB812G-100UG
Alexa Fluor 532
FAB812X
Alexa Fluor 594
FAB812T-100UG
Alexa Fluor 647
FAB812R-100UG
Alexa Fluor 700
FAB812N-100UG
Alexa Fluor 750
FAB812S-100UG
Allophycocyanin
FAB812A
Allophycocyanin/Cy7
FAB812APCCY7
Biotin
FAB812B
CoraFluor 1
FAB812CL1
DyLight 350
FAB812D
DyLight 405
FAB812E
DyLight 488
FAB812K
DyLight 550
FAB812L
DyLight 594
FAB812M
DyLight 650
FAB812W
DyLight 680
FAB812Y
DyLight 755
FAB812Z
HRP
FAB812H
Janelia Fluor 525
FAB812JF525
Janelia Fluor 549
FAB812I
Janelia Fluor 646
FAB812J
Janelia Fluor 669
FAB812JF669
PE/Atto594
FAB812PEATT594
PE/Cy5.5
FAB812PECY55
PE/Cy7
FAB812PECY7
PerCP
FAB812C
Phycoerythrin
FAB812P
Unconjugated
MAB812-100
mFluor Violet 500 SE
FAB812MFV500
mFluor Violet 610 SE
FAB812MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB812-100
Carrier Free
FAB812P
Carrier Free
FAB812A
Carrier Free
MAB812-SP
Carrier Free
MAB812-500
Carrier Free
MAB812-100
Carrier Free
FAB812V-100UG
Carrier Free
FAB812U-100UG
Carrier Free
FAB812T-100UG
Carrier Free
FAB812S-100UG
Carrier Free
FAB812R-100UG
Carrier Free
FAB812G-100UG
Carrier Free
FAB812N-100UG
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Flt-3/Flk-2/CD135 Antibody (66903) [mFluor Violet 450 SE] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human Flt‑3/Flk‑2
Asn27-Asn541
Accession # AAA18947
Specificity
Detect human Flt‑3/Flk‑2 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse Flt-3, recombinant human (rh) SCF R, rhPDGF R alpha , or rhPDGF R beta is observed.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
FLT3
Innovator's Reward
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Flt-3/Flk-2/CD135 Antibody (66903) [mFluor Violet 450 SE]

  • CD135 antigen
  • CD135
  • EC 2.7.10
  • fetal liver kinase 2
  • FL cytokine receptor
  • FLK2
  • Flk-2
  • FLT3 receptor tyrosine kinase
  • Flt3
  • Flt-3
  • Fms-like tyrosine kinase 3
  • fms-related tyrosine kinase 3
  • growth factor receptor tyrosine kinase type III
  • Stem cell tyrosine kinase 1
  • STK-1
  • STK1EC 2.7.10.1
  • Tyrosine-protein kinase receptor FLT3

Background

Stem cell tyrosine kinase (STK-1) has been cloned from a CD34+ hematopoietic stem cell enriched library and identified as the human homolog of a previously identified gene of mouse origin designated either Flk-2 or Flt-3. The STK-1 cDNA encodes a protein of 993 amino acids with 85% identity to Flt-3/Flk-2. STK-1 is a member of the type III receptor tyrosine kinase family that includes Kit (steel factor receptor), Fms and PDGF. STK-1 expression in blood and marrow is restricted to CD34+ cells, a population greatly enriched for hematopoietic stem/progenitor cells. STK-1 antiserum recognizes two polypeptides in these cells. The mouse homolog of STK-1, designated Flt-3/ Flk-2, is expressed at high levels in hematopoietic cells and also in neural, gonadal, hepatic and placental tissues. It has been suggested that STK-1 and its murine homolog Flt-3/ Flk-2 may function as growth factor receptors on hematopoietic stem and/or progenitor cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol FLT3