Ferritin Light Chain Antibody

This gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes. [provided by RefSeq]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 3 confirmed species: Human, Mouse, Rat.

We have publications tested in 1 application: WB.

Showing Publications 1 - 7 of 7.

Publications using NBP1-06986	Applications	Species
Fisher A, Wang C, Xu Y et al. Quantitative proteomics and RNA-sequencing of mouse liver endothelial cells identify novel regulators of BMP6 by iron iScience 2023-12-01 [PMID: 38125029]
Xiao X, Moschetta GA, Xu Y et al. Regulation of iron homeostasis by hepatocyte TFR1 requires HFE and contributes to hepcidin suppression in beta -thalassemia Blood 2022-11-02 [PMID: 36322932] (WB, Mouse)	WB	Mouse
Fisher AL, Srole DN, Palaskas NJ et al. Iron loading induces cholesterol synthesis and sensitizes endothelial cells to TNF?-mediated apoptosis Journal of Biological Chemistry 2021-10-01 [PMID: 34480898] (WB)	WB
AL Fisher, V Sangkhae, K Balušíková, NJ Palaskas, T Ganz, E Nemeth Iron-dependent apoptosis causes embryotoxicity in inflamed and obese pregnancy Nature Communications, 2021-06-29;12(1):4026. 2021-06-29 [PMID: 34188052]
Nam H, Wang CY, Zhang L et al. ZIP14 and DMT1 in the liver, pancreas, and heart are differentially regulated by iron deficiency and overload: implications for tissue iron uptake in iron-related. Haematologica 2013-01-24 [PMID: 23349308] (WB, Human)	WB	Human
Gu J, Xu H, Han Y, Dai W, Hao W, Wang C, Gu N, Xu H, Cao J. The internalization pathway, metabolic fate and biological effect of superparamagnetic iron oxide nanoparticles in the macrophage-like RAW2647 cell. Sci China Life Sci;54(9):793-805. 2011-09-01 [PMID: 21922429] (WB, Rat)	WB	Rat
Sammarco MC, Ditch S, Banerjee A, Grabczyk E. Ferritin L and H subunits are differentially regulated on a post-transcriptional level. J Biol Chem 2008-02-22 [PMID: 18160403]

Array NBP1-06986

• Ferritin Light Chain Antibodies
• Ferritin Light Chain ELISA Kits
• Ferritin Light Chain Lysate
• Ferritin Light Chain Proteins