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Fer Antibody [FITC]

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Product Details

Summary
Reactivity Hu, Mu, CaSpecies Glossary
Applications WB, ICC/IF, KD
Clonality
Polyclonal
Host
Rabbit
Conjugate
FITC

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP1-20089AF350
Alexa Fluor 405
NBP1-20089AF405
Alexa Fluor 488
NBP1-20089AF488
Alexa Fluor 532
NBP1-20089AF532
Alexa Fluor 594
NBP1-20089AF594
Alexa Fluor 647
NBP1-20089AF647
Alexa Fluor 700
NBP1-20089AF700
Alexa Fluor 750
NBP1-20089AF750
Allophycocyanin
NBP1-20089APC
Biotin
NBP1-20089B
CoraFluor 1
NBP1-20089CL1
DyLight 350
NBP1-20089UV
DyLight 405
NBP1-20089V
DyLight 488
NBP1-20089G
DyLight 550
NBP1-20089R
DyLight 594
NBP1-20089DL594
DyLight 650
NBP1-20089C
DyLight 680
NBP1-20089FR
DyLight 755
NBP1-20089IR
HRP
NBP1-20089H
Janelia Fluor 525
NBP1-20089JF525
Janelia Fluor 549
NBP1-20089JF549
Janelia Fluor 585
NBP1-20089JF585
Janelia Fluor 635
NBP1-20089JF635
Janelia Fluor 646
NBP1-20089JF646
Janelia Fluor 669
NBP1-20089JF669
PE
NBP1-20089PE
PerCP
NBP1-20089PCP
Unconjugated
NBP1-20089
mFluor Violet 450 SE
NBP1-20089MFV450
mFluor Violet 500 SE
NBP1-20089MFV500
mFluor Violet 610 SE
NBP1-20089MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-20089
BSA Free
NBP1-20089SS
BSA Free
NBP1-20089
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Fer Antibody [FITC] Summary

Immunogen
Synthetic peptide made to an internal portion of human FER (within residues 400-450). [Swiss-Prot# P16591]
Localization
Cytoplasm.
Predicted Species
Mouse (100%), Canine (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
FER
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Knockdown Validated
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Predicted to react with mouse and canine based on 100% sequence homology.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Fer Antibody [FITC]

  • EC 2.7.10
  • EC 2.7.10.2
  • fer (fps/fes related) tyrosine kinase
  • Fer
  • p94-Fer
  • Phosphoprotein NCP94
  • Proto-oncogene c-Fer
  • TYK3
  • TYK3phosphoprotein NCP94
  • Tyrosine kinase 3
  • tyrosine-protein kinase Fer

Background

FER (Feline sarcoma related) is a ubiquitously expressed non-receptor protein tyrosine kinase with about 94-kD size that acts downstream of cell surface receptors for growth factors and plays a key role in regulating actin cytoskeleton, microtubule assembly, lamellipodia formation, cell adhesion, cell migration and chemotaxis. It acts downstream of EGFR, KIT, FCER1, PDGFRA/PDGFRB receptor etc and phosphorylates CTTN, CTNND1, PTK2/FAK1, GAB1, PECAM1, PTPN11, JUP, PTPN1 and STAT3. Similar to other tyrosine kinases, FER has a central Src-homology 2 (SH2) domain involved in binding to phosphotyrosine-containing peptide sequences and a highly conserved C-terminal kinase domain, whereas it is different by an NH2-terminal FER/ClP4 homology and adjacent coiled-coil domains. FER is expressed ubiquitously in human tissues and higher FER levels are observed in cancer cells compared with adjacent normal cells e.g. renal cell carcinoma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol FER