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FBXW7/Cdc4 Antibody [Janelia Fluor® 585]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IP, WB (-)
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 585

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-88138AF350
Alexa Fluor 405
NB100-88138AF405
Alexa Fluor 488
NB100-88138AF488
Alexa Fluor 532
NB100-88138AF532
Alexa Fluor 594
NB100-88138AF594
Alexa Fluor 647
NB100-88138AF647
Alexa Fluor 700
NB100-88138AF700
Alexa Fluor 750
NB100-88138AF750
Allophycocyanin
NB100-88138APC
Biotin
NB100-88138B
CoraFluor 1
NB100-88138CL1
DyLight 350
NB100-88138UV
DyLight 405
NB100-88138V
DyLight 488
NB100-88138G
DyLight 550
NB100-88138R
DyLight 594
NB100-88138DL594
DyLight 650
NB100-88138C
DyLight 680
NB100-88138FR
DyLight 755
NB100-88138IR
FITC
NB100-88138F
HRP
NB100-88138H
Janelia Fluor 525
NB100-88138JF525
Janelia Fluor 549
NB100-88138JF549
Janelia Fluor 635
NB100-88138JF635
Janelia Fluor 646
NB100-88138JF646
Janelia Fluor 669
NB100-88138JF669
PE
NB100-88138PE
PerCP
NB100-88138PCP
Unconjugated
NB100-88138
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FBXW7/Cdc4 Antibody [Janelia Fluor® 585] Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 1 and 50 of human F-box and WD-40 domain protein 7 using the numbering given in entry NP_361014.1 (GeneID 55294).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
FBXW7
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunoprecipitation
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for FBXW7/Cdc4 Antibody [Janelia Fluor® 585]

  • AGO
  • AGOFBXO30
  • Archipelago Homolog
  • archipelago, Drosophila, homolog of
  • Cdc4
  • CDC4FLJ16457
  • F-box and WD repeat domain containing 7
  • F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila)
  • F-box and WD-40 domain-containing protein 7
  • F-box protein FBW7
  • F-box protein FBX30
  • F-box protein SEL-10
  • F-box/WD repeat-containing protein 7
  • FBW6
  • Fbw7
  • FBW7hCdc4
  • FBX30
  • FBX30FLJ11071
  • FBXO30
  • FBXW6
  • FBXW7
  • hAgo
  • homolog of C elegans sel-10
  • SCF(Fbw7)
  • SEL10
  • SEL-10DKFZp686F23254
  • SEL10FBW6

Background

Auxin-inducible degron (AID) technology allows rapid depletion of proteins in animal cells and fungi. Auxin includes chemicals such as IAA (indole-3-aceticacid) and NAA (1-naphtalene acetic acid) and includes inhibitors in plants. For the degradation, and SCF ubiquitin ligase complex containing the TIR1 protein is activated via the association of auxin with TIR1. Because the core SCF components are conserved in all eukaryotic cells, it is possible to transplant the degradation pathway to yeast and mammalian cells by expressing TIR1. In those cells expressing TIR1, a protein fused with degron (AID degron) derived from AUX/IAA can be rapidly degraded in the presence of auxin. Anti-mini-AID tag can detected both mini-AID-tag and full-length AID-tag.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FBXW7/Cdc4
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NB100-88138JF585
FBXW7/Cdc4 Antibody [Janelia Fluor® 585]
Species: Hu
Applications: IP, WB (-)

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Bioinformatics

Gene Symbol FBXW7