Species: Hu, Mu
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, IHC
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Description
Auxin-inducible degron (AID) technology allows rapid depletion of proteins in animal cells and fungi. Auxin includes chemicals such as IAA (indole-3-aceticacid) and NAA (1-naphtalene acetic acid) and includes inhibitors in plants. For the degradation, and SCF ubiquitin ligase complex containing the TIR1 protein is activated via the association of auxin with TIR1. Because the core SCF components are conserved in all eukaryotic cells, it is possible to transplant the degradation pathway to yeast and mammalian cells by expressing TIR1. In those cells expressing TIR1, a protein fused with degron (AID degron) derived from AUX/IAA can be rapidly degraded in the presence of auxin. Anti-mini-AID tag can detected both mini-AID-tag and full-length AID-tag.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
Human
Human
Human
|
| Product By Gene ID |
55294 |
| Alternate Names |
- AGOFBXO30
- Archipelago homolog
- archipelago, Drosophila, homolog of
- CDC4FLJ16457
- F-box and WD repeat domain containing 7
- F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila)
- F-box and WD-40 domain-containing protein 7
- F-box protein FBW7
- F-box protein FBX30
- F-box protein SEL-10
- F-box/WD repeat-containing protein 7
- FBW7hCdc4
- FBX30FLJ11071
- FBXW6
- hAgo
- homolog of C elegans sel-10
- SEL-10DKFZp686F23254
- SEL10FBW6
|
