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Exostosin-like 3/EXTL3 Antibody [Biotin]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Goat
Conjugate
Biotin
Concentration
LYOPH

Order Details

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Catalog# & Conjugate Size Price
Unconjugated
AF2635
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
AF2635
Carrier Free
AF2635
Carrier Free
AF2635-SP
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Exostosin-like 3/EXTL3 Antibody [Biotin] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human Exostosin-like 3/EXTL3 Lumenal Domain
Thr52-Ile919
Accession # O43909
Specificity
Detects human Exostosin-like 3/EXTL3 lumenal domain in Western blots. In Western blots, less than 1% cross-reactivity with recombinant human EXTL1 is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
EXTL3
Purity Statement
Antigen Affinity-purified
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Applications/Dilutions

Dilutions
  • Western Blot 0.1 ug/mL
Readout System

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Exostosin-like 3/EXTL3 Antibody [Biotin]

  • botv
  • DKFZp686C2342
  • EC 2.4.1.223
  • exostoses (multiple)-like 3
  • Exostosin like 3
  • Exostosin-like 3
  • EXTL1L
  • EXTL3
  • EXTR1BOTV
  • EXT-related protein 1
  • Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase
  • Hereditary multiple exostoses gene isolog
  • KIAA0519
  • Multiple exostosis-like protein 3
  • Putative tumor suppressor protein EXTL3
  • reg receptor
  • REG
  • REGR
  • RPR

Background

Exostosin-like 3 (EXTL3) is an ER-resident type II transmembrane protein belonging to the EXT family of tumor suppressor genes. EXT family members are glycosyl transferases that are involved in the synthesis of the glycosaminoglycan chains of heparan sulfate proteoglycans. EXTL3 was also reported to be a receptor for the REG protein, a pancreatic beta-cell regeneration factor. The lumenal domains of human, mouse and rat share 97% amino acid sequence identity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol EXTL3
Uniprot