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EXOSC3 Antibody

Images

 
Western Blot: EXOSC3 Antibody [NBP2-16392] - Sample (30 ug of whole cell lysate) A: A431 B: JurKat C: Raji 12% SDS PAGE gel, diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: EXOSC3 Antibody [NBP2-16392] - Confocal immunofluorescence analysis of paraformaldehyde-fixed HeLa, using EXOSC3 antibody (Green) at 1:500 dilution. Alpha-tubulin filaments are ...read more
Immunohistochemistry-Paraffin: EXOSC3 Antibody [NBP2-16392] - HeLa xenograft. EXOSC3 antibody dilution: 1:500. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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EXOSC3 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human EXOSC3. The exact sequence is proprietary.
Localization
Cytoplasm; Nucleus; nucleolus
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
EXOSC3
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:100-1:1000
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
Theoretical MW
30 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol
Preservative
0.01% Thimerosal
Purity
Antigen Affinity-purified

Alternate Names for EXOSC3 Antibody

  • bA3J10.7
  • CGI-102
  • exosome complex exonuclease RRP40
  • exosome component 3MGC15120
  • exosome component Rrp40
  • hRrp-40
  • hRrp40p
  • p10Rrp40p
  • Ribosomal RNA-processing protein 40
  • RP11-3J10.8
  • RRP40MGC723

Background

EXOSC3 is a component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions. Required for the 3'processing of the 7S pre-RNA to the mature 5.8S rRNA. Ha

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for EXOSC3 Antibody (NBP2-16392) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol EXOSC3
Uniprot