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EPS15 Antibody (1261C) [Janelia Fluor® 585]

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      FAB8480JF585
    • Availability
      Product Discontinued

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EPS15 Antibody (1261C) [Janelia Fluor® 585] Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
E.coli-derived recombinant human Eps15
Ala448-Thr579
Accession # P42566
Specificity
Detects human Eps15 in direct ELISAs and Western blots.
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
EPS15
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry
  • Intracellular Staining by Flow Cytometry
  • Simple Western
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for EPS15 Antibody (1261C) [Janelia Fluor® 585]

  • AF1P
  • AF-1P
  • ALL1 fused gene from chromosome 1
  • epidermal growth factor receptor pathway substrate 15
  • epidermal growth factor receptor substrate 15
  • Eps15
  • MLLT5
  • Protein AF-1p
  • Protein Eps15

Background

EPS15 is a ubiquitously expressed protein that is involved in cell growth regulation and may be involved in the regulation of mitogenic signals and control of cell proliferation. EPS15 may be phosphorylated on tyrosine 849 following DNA damage, resulting in the internalization of EGFR. A chromosomal aberration involving EPS15 is also found in acute myelogeneous leukemias, resulting in a rogue activator protein, so EPS15 antibodies may be useful for cancer research.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

Additional EPS15 Products

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Bioinformatics

Gene Symbol EPS15