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Epac2 Antibody (1C11)

Images

 
Western Blot: Epac2 Antibody (1C11) [H00011069-M01] - Analysis of RAPGEF4 expression in transfected 293T cell line by RAPGEF4 monoclonal antibody (M01), clone 1C11.Lane 1: RAPGEF4 transfected lysate (Predicted MW: 115.5 ...read more
Sandwich ELISA: Epac2 Antibody (1C11) [H00011069-M01] - Detection limit for recombinant GST tagged RAPGEF4 is approximately 0.3ng/ml as a capture antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
1C11
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

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Epac2 Antibody (1C11) Summary

Immunogen
RAPGEF4 (AAH24004, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MVAAHAAHSSSSAEWIACLDKRPLERSSEDVDIIFTRLKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIG
Specificity
RAPGEF4 - Rap guanine nucleotide exchange factor (GEF) 4
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
RAPGEF4
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Sandwich ELISA
  • Western Blot 1:500
Application Notes
Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Epac2 Antibody (1C11)

  • cAMP-GEFII
  • cAMP-regulated guanine nucleotide exchange factor II
  • CGEF2
  • CGEF2EPAC 2
  • EPAC 2
  • Epac2
  • Exchange factor directly activated by cAMP 2
  • Exchange protein directly activated by cAMP 2
  • Nbla00496
  • putative protein product of Nbla00496
  • Rap guanine nucleotide exchange factor (GEF) 4
  • rap guanine nucleotide exchange factor 4
  • RAP guanine-nucleotide-exchange factor (GEF) 4
  • RAPGEF4

Background

Epac2, also known as Rap Guanine Nucleotide Exchange Factor (GEF) 4, is a guanine nucleotide exchange factor for RAP1A, RAP1B and RAP2A small GTPases. Studies have shown that EPAC2 has a significant role in the development of type 2 diabetes. EPAC2 has also been studied in relation to ataxia, neuronitis, osteoporosis and pancreatitis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol RAPGEF4
Entrez
OMIM
Uniprot