Home » Endorepellin/Perlecan/Heparan Sulfate Proteoglycan » Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Antibodies » Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Antibody (SPM255) [mFluor Violet 450 SE]
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Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Antibody (SPM255) [mFluor Violet 450 SE]

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Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Antibody (SPM255) [mFluor Violet 450 SE] [NBP3-11461MFV450] - Vial of mFluor Violet 450 conjugated antibody. mFluor Violet 450 is optimally excited at 406 nm by the Violet laser (405 nm) and has an emission maximum of 445 nm.
Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Antibody (SPM255) [mFluor Violet 450 SE] [NBP3-11461MFV450] - Vial of mFluor Violet 450 conjugated antibody. mFluor Violet 450 is optimally excited at 406 nm by the ...read more

Product Details

Summary
Reactivity Hu, Mu, Po, Bv, Fi, PmSpecies Glossary
Applications Flow, ICC/IF, IHC, ICC/IF
Clone
SPM255
Clonality
Monoclonal
Host
Rat
Conjugate
mFluor Violet 450 SE

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-11461AF350
Alexa Fluor 405
NBP3-11461AF405
Alexa Fluor 488
NBP3-11461AF488
Alexa Fluor 532
NBP3-11461AF532
Alexa Fluor 594
NBP3-11461AF594
Alexa Fluor 647
NBP3-11461AF647
Alexa Fluor 700
NBP3-11461AF700
Alexa Fluor 750
NBP3-11461AF750
Allophycocyanin
NBP3-11461APC
Biotin
NBP3-11461B
CoraFluor 1
NBP3-11461CL1
DyLight 350
NBP3-11461UV
DyLight 405
NBP3-11461V
DyLight 488
NBP3-11461G
DyLight 550
NBP3-11461R
DyLight 594
NBP3-11461DL594
DyLight 650
NBP3-11461C
DyLight 680
NBP3-11461FR
DyLight 755
NBP3-11461IR
FITC
NBP3-11461F
HRP
NBP3-11461H
Janelia Fluor 525
NBP3-11461JF525
Janelia Fluor 549
NBP3-11461JF549
Janelia Fluor 585
NBP3-11461JF585
Janelia Fluor 635
NBP3-11461JF635
Janelia Fluor 646
NBP3-11461JF646
Janelia Fluor 669
NBP3-11461JF669
PE
NBP3-11461PE
PerCP
NBP3-11461PCP
Unconjugated
NBP2-44449-0.1mg
mFluor Violet 500 SE
NBP3-11461MFV500
mFluor Violet 610 SE
NBP3-11461MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-44449-0.1mg
IHC-Prediluted
NBP2-48244
Azide and BSA Free
NBP3-11461
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Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Antibody (SPM255) [mFluor Violet 450 SE] Summary

Immunogen
Murine EHS laminin preparation
Localization
Basement membrane
Specificity
This monoclonal antibody specifically precipitates heterogeneous material of high MW, identified as perlecan, a major heparan-sulfate proteoglycan (HSPG) within all basement membranes and cell surfaces. It does not cross-react with laminin, fibronectin, or dermatran sulfate proteoglycan. Because of perlecans strategic location and ability to store and protect growth factors, it has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a co-receptor for basic fibroblast growth factor (FGF-2). Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplastic treatment.
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Rat
Gene
HSPG2
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Antibody (SPM255) [mFluor Violet 450 SE]

  • basement membrane-specific heparan sulfate proteoglycan core protein
  • endorepellin (domain V region)
  • heparan sulfate proteoglycan 2
  • Heparan Sulfate Proteoglycan
  • HSPG
  • perlecan proteoglycan
  • perlecan
  • PLCSchwartz-Jampel syndrome 1 (chondrodystrophic myotonia)
  • PRCAN
  • SJA
  • SJS
  • SJS1

Background

Perlecan is an extracellular matrix proteoglycan. It has a large core protein of 400-450 kDa and is often produced with heparan sulfate side chains. Perlecan is found in basement membranes where it contributes to the permeability characteristics, serves as a substrate for vascular cells and binds growth factors involved in vascular remodeling (2).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Endorepellin/Perlecan/ ...
NBP3-11461MFV450
Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Antibody (SPM255) [mFluor Violet 450 SE]
Species: Hu, Mu, Po, Bv, Fi, Pm
Applications: Flow, ICC/IF, IHC, ICC/IF

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mFluor Violet Conjugated Antibodies

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Bioinformatics

Gene Symbol HSPG2