Recombinant Human eIF2 alpha/EIF2S1 His Protein

EIF2S1, also known as eIF2 alpha, is the alpha subunit of the translation initiation factor eIF2 complex which catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. The phosphorylation state of eIF2S1 controls the rate of tRNA translation. When eIF2 alpha is not phosphorylated, translation occurs at a normal rate. However, upon phosphorylation by one of several kinases, eIF2S1 is stabilized, thus preventing the GDP/GTP exchange reaction and slowing translation. Recombinant human EIF2S1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: PAGE.

Showing Publication 1 - 1 of 1.

Publication using NBP1-44467	Applications	Species
Tang Y, Zhang S, Li J et al. ID1 marks the tumorigenesis of pancreatic ductal adenocarcinoma in mouse and human Scientific reports 2022-08-08 [PMID: 35941362] (PAGE, Human)	PAGE	Human

Array NBP1-44467

• eIF2 alpha/EIF2S1 Antibodies
• eIF2 alpha/EIF2S1 Lysate
• eIF2 alpha/EIF2S1 Proteins