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EBI3 Antibody (607201) [DyLight 550]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications CyTOF-ready, Flow
Clone
607201
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 550

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB6456U
Alexa Fluor 350
IC6456U-100UG
Alexa Fluor 405
IC6456V-100UG
Alexa Fluor 405
FAB6456V
Alexa Fluor 488
IC6456G
Alexa Fluor 488
FAB6456G
Alexa Fluor 532
FAB6456X
Alexa Fluor 594
FAB6456T
Alexa Fluor 594
IC6456T-100UG
Alexa Fluor 647
IC6456R-100UG
Alexa Fluor 647
FAB6456R
Alexa Fluor 700
FAB6456N
Alexa Fluor 700
IC6456N-100UG
Alexa Fluor 750
IC6456S-100UG
Alexa Fluor 750
FAB6456S
Allophycocyanin
FAB6456A
Allophycocyanin
IC6456A
Biotin
FAB6456B
DyLight 350
FAB6456D
DyLight 405
FAB6456E
DyLight 488
FAB6456K
DyLight 594
FAB6456M
DyLight 650
FAB6456W
DyLight 680
FAB6456Y
DyLight 755
FAB6456Z
FITC
FAB6456F
HRP
FAB6456H
Janelia Fluor 549
FAB6456I
Janelia Fluor 646
FAB6456J
PE
FAB6456P
PerCP
FAB6456C
Unconjugated
MAB6456
mFluor Violet 450 SE
FAB6456MFV450
mFluor Violet 500 SE
FAB6456MFV500
mFluor Violet 610 SE
FAB6456MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB6456
Carrier Free
MAB6456
Carrier Free
IC6456A
Carrier Free
IC6456G
Carrier Free
MAB6456-SP
Carrier Free
IC6456N-100UG
Carrier Free
IC6456V-100UG
Carrier Free
IC6456U-100UG
Carrier Free
IC6456T-100UG
Carrier Free
IC6456S-100UG
Carrier Free
IC6456R-100UG
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EBI3 Antibody (607201) [DyLight 550] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human IL-27/IL-35 EBI3 Subunit
Arg21-Lys229 (predicted)
Accession # Q14213
Specificity
Detects human IL-27/IL-35 EBI3 Subunit in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse (rm) IL-27 EBI3 or rmIL-27 (EBI3 + p28 heterodimer) is observed.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
EBI3
Purity
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Intracellular Staining by Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for EBI3 Antibody (607201) [DyLight 550]

  • cytokine receptor
  • EBI3
  • EBI-3
  • EBV-induced gene 3 protein
  • Epstein-Barr virus induced 3
  • Epstein-Barr virus induced gene 3
  • Epstein-Barr virus-induced gene 3 protein
  • IL-27 beta
  • IL-27 subunit beta
  • IL27B
  • IL-27B
  • IL35 EBI3
  • IL-35 EBI3
  • interleukin-27 subunit beta

Background

EBI3 gene encodes a 229 amino acid long, 25 kDA interleukin-27 subunit beta protein that is member to the hematopoitetin receptor family. These proteins obtain pro as well as anti-inflammatory properties and have roles in T-helper cell development, suppressing cell proliferation, encouraging cytotoxic T-cell activity, and can induce isotope switching in B cells. EBI3 participates in Th1 differentiation, IL-2 signaling (and its primary biological effects in various immune cells), as well as IL27-mediated signaling events. EBI3 interacts with genes IL27, IL12A, CANX, MDF1, and SMAD3. It has been associated and researched in sepsis, asthma, carcinoma, Chron's disease, b-cell lymphomas, ulcerative colitis, Hodgkin disease, lymphoma, ebv infections, and glomerulonephritis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs for EBI3 Antibody (FAB6456L) (0)

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Secondary Antibodies

 

Isotype Controls

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Research Areas for EBI3 Antibody (FAB6456L)

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Blogs on EBI3

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Contact Information

Product PDFs

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  PDF Datasheet
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Calculators

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Bioinformatics

Gene Symbol EBI3