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Dopamine D2R/DRD2 Antibody

Images

 
Western Blot: Dopamine D2R/DRD2 Antibody [NBP2-88996] - MW marker (1) and 10ug of rat heart membrane extract (2) probed with Dopamine Receptor (D2) pAb at 4.0ug/ml.
Immunohistochemistry: Dopamine D2R/DRD2 Antibody [NBP2-88996] - Rat cerebral cortex. Neurons are labeled with Dopamine Receptor (D2) pAb in conjunction with Cy3 conjugated rabbit IgG antibody (H+L).
ELISA: Dopamine D2R/DRD2 Antibody [NBP2-88996] - HEK293 cells expressing dopamine receptor (D2) were treated with indicated concentrations of agonist (Quinpirol) and antagonist (Siperone) and probed with Dopamine ...read more
Western Blot: Dopamine D2R/DRD2 Antibody [NBP2-88996] - Dopamine D2R/DRD2 antibody [NBP2-88996]. Left image is the MW marker and right is two replicates of ~20 ug protein extract from one hemisphere of house sparrow ...read more

Product Details

Summary
Reactivity Hu, Mu, Rt, AvSpecies Glossary
Applications WB, ELISA, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Dopamine D2R/DRD2 Antibody Summary

Immunogen
Synthetic peptide corresponding to the sequence near the N-terminus of mouse Dopamine D2R/DRD2.
Clonality
Polyclonal
Host
Rabbit
Gene
DRD2
Purity
Peptide affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry
  • Western Blot
Theoretical MW
51 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Reviewed Applications
Read 1 Review rated 4
using
NBP2-88996 in the following applications:

Reactivity Notes

Predicted species reactivity based on epitope sequence homology: rhesus macaque, chimpanzee, horse, arctic fox, dog, opossum, ferret. Avian reactivity reported from a verified customer review.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS containing 50% glycerol
Preservative
0.01% Sodium Azide
Purity
Peptide affinity purified

Alternate Names for Dopamine D2R/DRD2 Antibody

  • D(2) dopamine receptor
  • D2DR
  • D2R
  • Dopamine D2 R
  • Dopamine D2 receptor
  • Dopamine D2R
  • dopamine receptor D2 isoform
  • dopamine receptor D2
  • DRD2
  • seven transmembrane helix receptor

Background

The DRD2 Dopamine Receptor is involved in the neuromodulation of appetitive behaviors. DRD2 may be linked to alcoholism and other substance-use disorders. Mutations in DRD2 in mice lead to the suppression of reward behavior with morphine and to the reduction of spontaneous movements, a phenotype resembling Parkinson's disease. Three alternatively spliced isoforms have been identified. DRD2 has been reported to be expressed in various regions of the brain, as well as in aorta, artery, eye, and spinal cord. ESTs have been isolated from normal pituitary and in brain, colon, lung, pancreas, and skeletal muscle cancer libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Dopamine D2R/DRD2 Antibody (NBP2-88996) (0)

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Review for Dopamine D2R/DRD2 Antibody (NBP2-88996) (1) 41

Average Rating: 4
(Based on 1 review)
We have 1 review tested in 1 species: Avian and House sparrow.

Reviews using NBP2-88996:
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(1)
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Images Ratings Applications Species Date Details
  4
reviewed by:
Melanie Kimball
WB Avian and House sparrow 06/16/2023
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Summary

ApplicationWestern Blot
Sample TestedAdult brain
SpeciesAvian and House sparrow
Lot08202104

Comments

Comments***Novus Innovators Program - new species or application used on a primary antibody.***

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Recent Reviews

4
5
0
4
1
3
0
2
0
1
0

Melanie Kimball
06/16/2023
Application: WB
Species: Avian and House sparrow

Bioinformatics

Gene Symbol DRD2