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DMC1 Antibody (2H12/4) [Janelia Fluor® 669]

Name: DMC1 Antibody (2H12/4) [Janelia Fluor&#174; 669]
Brand: Novus Biologicals
SKU: NB100-2617JF669
Price: 499 USD

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Product Details

Summary

Reactivity	Hu, Mu, BvSpecies Glossary
Applications	WB, Flow, ICC/IF, IHC, IP
Clone	2H12/4
Clonality	Monoclonal
Host	Mouse
Conjugate	Janelia Fluor 669

Order Details

View Available Conjugates

Catalog# & Conjugate	Size	Price
Alexa Fluor 350 NB100-2617AF350

Alexa Fluor 405 NB100-2617AF405

Alexa Fluor 488 NB100-2617AF488

Alexa Fluor 532 NB100-2617AF532

Alexa Fluor 594 NB100-2617AF594

Alexa Fluor 647 NB100-2617AF647

Alexa Fluor 700 NB100-2617AF700

Alexa Fluor 750 NB100-2617AF750

Biotin NB100-2617B

CoraFluor 1 NB100-2617CL1

DyLight 350 NB100-2617UV

DyLight 405 NB100-2617V

DyLight 488 NB100-2617G

DyLight 550 NB100-2617R

DyLight 594 NB100-2617DL594

DyLight 650 NB100-2617C

DyLight 680 NB100-2617FR

DyLight 755 NB100-2617IR

FITC NB100-2617F

HRP NB100-2617H

Janelia Fluor 525 NB100-2617JF525

Janelia Fluor 549 NB100-2617JF549

Janelia Fluor 646 NB100-2617JF646

Unconjugated NB100-2617

mFluor Violet 450 SE NB100-2617MFV450

mFluor Violet 500 SE NB100-2617MFV500

mFluor Violet 610 SE NB100-2617MFV610

View Available Formulations

Catalog# & Formulation	Size	Price
Standard Formulation NB100-2617

BSA Free NB100-2617

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Conjugate	Catalog #	Availability	Size	Price
Alexa Fluor 350	NB100-2617AF350
Alexa Fluor 405	NB100-2617AF405
Alexa Fluor 488	NB100-2617AF488
Alexa Fluor 532	NB100-2617AF532
Alexa Fluor 594	NB100-2617AF594
Alexa Fluor 647	NB100-2617AF647
Alexa Fluor 700	NB100-2617AF700
Alexa Fluor 750	NB100-2617AF750
Biotin	NB100-2617B
CoraFluor 1	NB100-2617CL1
DyLight 350	NB100-2617UV
DyLight 405	NB100-2617V
DyLight 488	NB100-2617G
DyLight 550	NB100-2617R
DyLight 594	NB100-2617DL594
DyLight 650	NB100-2617C
DyLight 680	NB100-2617FR
DyLight 755	NB100-2617IR
FITC	NB100-2617F
HRP	NB100-2617H
Janelia Fluor 525	NB100-2617JF525
Janelia Fluor 549	NB100-2617JF549
Janelia Fluor 646	NB100-2617JF646
Unconjugated	NB100-2617
mFluor Violet 450 SE	NB100-2617MFV450
mFluor Violet 500 SE	NB100-2617MFV500
mFluor Violet 610 SE	NB100-2617MFV610

DMC1 Antibody (2H12/4) [Janelia Fluor® 669] Summary

Immunogen	Human DMC1 protein (expressed as 6xHis fusion in E. coli and band cut out of gel of insoluble pelet)
Localization	Nuclear
Specificity	Specific for DMC1 - does not cross-react with the related protein Rad51.
Isotype	IgG2a
Clonality	Monoclonal
Host	Mouse
Gene	DMC1
Purity	Protein A purified
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Applications/Dilutions

Dilutions	Flow Cytometry Immunocytochemistry/ Immunofluorescence Immunohistochemistry Immunoprecipitation Western Blot
Application Notes	Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

Storage	Store at 4C in the dark.
Buffer	50mM Sodium Borate
Preservative	0.05% Sodium Azide
Purity	Protein A purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for DMC1 Antibody (2H12/4) [Janelia Fluor® 669]

disrupted meiotic cDNA1, yeast, homolog of
DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologousrecombination (yeast)
DMC1 homologue
HsLim15
LIM15yeast homolog) meiosis-specific homologousrecombination
meiotic recombination protein DMC1/LIM15 homolog
MGC150472
MGC150473

Background

DMC-1 is a meiosis-specific homologue of RecA/Rad51 and is an essential component of the meiotic recombination machinery in yeast and higher eukaryotes. DMC-1 is the human equivalent of e. coli recA.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

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Research Areas for DMC1 Antibody (NB100-2617JF669)

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Blogs on DMC1.

Check out the latest blog posts on DMC1.

Determining DMC1's role in Homologus Recombination
The DMC1 gene encodes a 36.7 kDa nuclear protein involved in meiotic homologous recombination. This recombinase is functionally related to the yeast RAD51 and E. coli RecA genes. In contrast to RAD51, which functions in both mitotic and meiotic recomb... Read full blog post.

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Bioinformatics

Gene Symbol

DMC1

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

DMC1 Antibody (2H12/4) [Janelia Fluor® 669]

Species Glossary

Images

Product Details

Order Details

DMC1 Antibody (2H12/4) [Janelia Fluor® 669] Summary

Applications/Dilutions

Reactivity Notes

Packaging, Storage & Formulations

Notes

Alternate Names for DMC1 Antibody (2H12/4) [Janelia Fluor® 669]

Background

Limitations

Customers Who Viewed This Item Also Viewed...

Publications for DMC1 Antibody (NB100-2617JF669) (0)

Reviews for DMC1 Antibody (NB100-2617JF669) (0)

Product General Protocols

Video Protocols

FAQs for DMC1 Antibody (NB100-2617JF669) (0)

Secondary Antibodies

Isotype Controls

Additional DMC1 Products

Research Areas for DMC1 Antibody (NB100-2617JF669)

Blogs on DMC1.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Review this Product

Bioinformatics