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DIS3 Antibody [CoraFluor™ 1]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
CoraFluor 1

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DIS3 Antibody [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Immunogen
DIS3 antibody was raised against an 18 amino acid peptide near the amino terminus of human DIS3. The immunogen is located within amino acids 90 - 140 of DIS3. Amino Acid Squence: YKRIRDVTNNQEKHFYTF
Specificity
Multiple isoforms of DIS3 are known to exist.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DIS3
Purity
Peptide affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Peptide affinity purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for DIS3 Antibody [CoraFluor™ 1]

  • 2810028N01Rik
  • DIS3 mitotic control homolog (S. cerevisiae)
  • dis3p
  • DKFZp667L1817
  • EC 3.1.13
  • EC 3.1.13.-
  • EC 3.1.26.-
  • EXOSC11
  • exosome complex exonuclease RRP44
  • exosome component 11
  • FLJ10484
  • KIAA1008RP11-342J4.3
  • MGC33035
  • mitotic control protein dis3 homolog
  • Protein DIS3 homolog
  • Ribosomal RNA-processing protein 44
  • RRP44bA555G22.1

Background

DIS3 is a component of the exosome 3'->5' exoribonuclease complex. Required for the 3'-processing of the 7S pre-RNA to the mature nuclear complex. Also associated with the GTPase Ran. Has a 3'-5' exonuclease activity

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for DIS3 Antibody (NBP2-81804CL1) (0)

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Secondary Antibodies

 

Isotype Controls

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Blogs on DIS3

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Bioinformatics

Gene Symbol DIS3