DIAPH1 Antibody

Diaphanous 1 is a member of the Formin homology (FH) family of cytoskeletal organizer proteins. It is required for cytokinesis and transcriptional activation of the serum response factor. It has also been suggested to contribute to localized actin polymerization and stress fiber formation, both by recruiting profiling to sites of Rho action and by cooperating with ROCK. The human Diaphanous 1 gene is associated with Premature Ovarian Failure (POF) and Nonsyndromic Deafness (DFNA1), an autosomal dominant, fully penetrant progressive hearing loss.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 4 of 4.

Publications using NB600-230	Applications	Species
Colon-Franco JM, Gomez TS, Billadeau DD et al. Dynamic remodeling of the actin cytoskeleton by FMNL1gammais required for structural maintenance of the Golgi complex. J Cell Sci 2011-09-01 [PMID: 21868368]
Ryu JR, Echarri A, Li R et al. Regulation of cell-cell adhesion by Abi/Diaphanous complexes. Mol Cell Biol 2009-04-01 [PMID: 19158278]
Sakata D, Taniguchi H, Yasuda S et al. Impaired T lymphocyte trafficking in mice deficient in an actin-nucleating protein, mDia1. J Exp Med. 2007-09-03 [PMID: 17682067] Details: WB (Fig 5B): primary T cells isolated from adult mouse spleen.
Minin AA, Kulik AV, Gyoeva FK et al. Regulation of mitochondria distribution by RhoA and formins. J Cell Sci 2006-02-01 [PMID: 16434478]

Array NB600-230

• DIAPH1 Antibodies
• DIAPH1 ELISA Kits
• DIAPH1 Lysates
• DIAPH1 Protein