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Desmoglein-3 Antibody (5H10) [Janelia Fluor® 646]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, DB, ICC/IF, IHC, IP
Clone
5H10
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 646

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Desmoglein-3 Antibody (5H10) [Janelia Fluor® 646] Summary

Immunogen
The extracellular domain of human Desmoglein 3 [Swiss-Prot# P32926]
Localization
Cell membrane; Single-pass type I membrane protein. Cell junction > desmosome
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
DSG3
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Dot Blot
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Desmoglein-3 Antibody (5H10) [Janelia Fluor® 646]

  • Cadherin family member 6
  • CDHF6
  • CDHF6130-kD pemphigus vulgaris antigen
  • desmoglein 3 (pemphigus vulgaris antigen)
  • desmoglein 3
  • Desmoglein3
  • Desmoglein-3
  • DKFZp686P23184,130 kDa pemphigus vulgaris antigen
  • DSG3
  • pemphigus vulgaris antigen
  • PVA

Background

Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Desmoglein-3 Antibody (NBP1-78984JF646) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol DSG3