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DDIT4L Antibody (DDIT-03) [DyLight 680]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow
Clone
DDIT-03
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 680

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DDIT4L Antibody (DDIT-03) [DyLight 680] Summary

Immunogen
N-terminal recombinant fragment of human DDIT4L (amino acids 2-98)
Specificity
The antibody MEM-18 reacts with CD14, a 53-55 kDa GPI (glycosylphosphatidylinositol)-linked membrane glycoprotein expressed on monocytes, macrophages and weakly on granulocytes; also expressed by most tissue macrophages. In human, the epitope recognized by MEM-18 is located between amino acids 57-64.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
DDIT4L
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow (Intracellular)
  • Flow Cytometry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for DDIT4L Antibody (DDIT-03) [DyLight 680]

  • DNA damage-inducible transcript 4-like protein
  • DNA-damage-inducible transcript 4-like
  • HIF-1 responsive protein RTP801-like
  • homolog of mouse SMHS1
  • Protein regulated in development and DNA damage response 2
  • REDD-2
  • REDD2Rtp801L
  • regulated in development and DNA damage response 2
  • RTP801L

Background

DDIT4L, also known as DNA damage-inducible transcript 4-like protein, is a 21.7 kDa 193 amino acid protein that regulates the TOR signaling pathway between the TSC1-TSC2 complex and AKT1, thus inhibiting cell growth. Current research is being conducted with diseases and disorders such as teratoma, melanoma, and hypoxia. The protein is involved in the TOR signaling pathway, where it interacts with SNRPG and PRKAB2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol DDIT4L