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Cytokeratin, HMW Antibody

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Immunohistochemistry-Paraffin: Cytokeratin, HMW Antibody [NBP2-97591] - Immunochemical staining of human Cytokeratin, HMW in human tonsil with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin ...read more
Immunohistochemistry-Paraffin: Cytokeratin, HMW Antibody [NBP2-97591] - Immunochemical staining of human Cytokeratin, HMW in human skin with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Cytokeratin, HMW Antibody Summary

Description
This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.
Immunogen
Produced in rabbits immunized with E. coli-derived Human Cytokeratin, HMW fragment.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KRT76
Purity
Antigen and protein A Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 1:200-1:1000

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.03% Proclin 300
Purity
Antigen and protein A Affinity-purified

Alternate Names for Cytokeratin, HMW Antibody

  • CK-2P
  • cytokeratin 2
  • Cytokeratin-2P
  • HUMCYT2A
  • K2P
  • K76
  • keratin 76
  • keratin, type II cytoskeletal 2 oral
  • keratin-76
  • KRT2Bcytokeratin-2P
  • KRT2Pkeratin 2p
  • KRT76
  • Type-II keratin Kb9

Background

KRT76, also known as Keratin, type II cytoskeletal 2 oral, is a 638 amino acid that is approx. 66 kDa, belongs to the intermediate filament family responsible for the structural integrity of epithelial cells, subdivided into epithelial keratins and hair keratins, and probably contributes to terminal cornification. Studies are being performed in relation to this protein and obstructive jaundice, pharyngitis, jaundice, cervical cancer, neuronitis, colorectal cancer, cervicitis, interferon and hepatitis. This protein has been shown to have interactions with ATG13, PDPK1, ULK2, GABARAP, and PRKAA1 in cytoskeleton organization pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol KRT76