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Complement Component C5aR1 Antibody (583837) [DyLight 405]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
583837
Clonality
Monoclonal
Host
Rat
Conjugate
DyLight 405

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB6467U-100UG
Alexa Fluor 405
FAB6467V-100UG
Alexa Fluor 488
FAB6467G-100UG
Alexa Fluor 532
FAB6467X
Alexa Fluor 594
FAB6467T-100UG
Alexa Fluor 647
FAB6467R-100UG
Alexa Fluor 700
FAB6467N-100UG
Alexa Fluor 750
FAB6467S-100UG
Allophycocyanin
FAB6467A
Allophycocyanin/Cy7
FAB6467APCCY7
Biotin
FAB6467B
CoraFluor 1
FAB6467CL1
DyLight 350
FAB6467D
DyLight 488
FAB6467K
DyLight 550
FAB6467L
DyLight 594
FAB6467M
DyLight 650
FAB6467W
DyLight 680
FAB6467Y
DyLight 755
FAB6467Z
FITC
FAB6467F
HRP
FAB6467H
Janelia Fluor 525
FAB6467JF525
Janelia Fluor 549
FAB6467I
Janelia Fluor 585
FAB6467JF585
Janelia Fluor 635
FAB6467JF635
Janelia Fluor 646
FAB6467J
Janelia Fluor 669
FAB6467JF669
PE
FAB6467P
PE/Atto594
FAB6467PEATT594
PE/Cy5.5
FAB6467PECY55
PE/Cy7
FAB6467PECY7
PerCP
FAB6467C
Unconjugated
MAB6467
mFluor Violet 450 SE
FAB6467MFV450
mFluor Violet 500 SE
FAB6467MFV500
mFluor Violet 610 SE
FAB6467MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB6467
Carrier Free
MAB6467
Carrier Free
FAB6467A
Carrier Free
MAB6467-SP
Carrier Free
FAB6467V-100UG
Carrier Free
FAB6467U-100UG
Carrier Free
FAB6467T-100UG
Carrier Free
FAB6467S-100UG
Carrier Free
FAB6467R-100UG
Carrier Free
FAB6467N-100UG
Carrier Free
FAB6467G-100UG
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Complement Component C5aR1 Antibody (583837) [DyLight 405] Summary

Immunogen
NS0 mouse myeloma cell line transfected with mouse Complement Component C5a R1
Accession # P30993
Specificity
This antibody detects mouse Complement Component C5a R1 via flow cytometry.
Isotype
IgG2b
Clonality
Monoclonal
Host
Rat
Gene
C5AR1
Purity
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Complement Component C5aR1 Antibody (583837) [DyLight 405]

  • C5a anaphylatoxin chemotactic receptor
  • C5A
  • C5aR
  • C5a-R
  • C5AR1
  • C5ARC5a anaphylatoxin receptor
  • C5R1C5a ligand
  • CD88 antigen
  • CD88
  • complement component 5 receptor 1 (C5a ligand)
  • complement component 5 receptor 1
  • complement component 5a receptor 1
  • Complement Component C5a R1
  • Complement Component C5aR1

Background

The human anaphylatoxin C5a is a 74 residue glycopeptide which is generated by proteolytic cleavage of the complement factor C5 in the course of complement activation. A variety of biological effects evoked by C5a can be demonstrated, rendering this molecule an important mediartor of inflammation, with granulocytes and macrophages as the main target cells. All cellular responses to C5a are specifically mediated by interactions with the membrane bound C5a receptor, a seven transmembrane GTP binding coupled receptor that belongs to the rhodopsin supergene family. C5a receptor 1 expression has been reported in myeloid blood cells, brain, liver, lung, spleen, heart, kidney, and intestinal tract. ESTs have been isolated from B cell/lung/testis, nerve, and placenta libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol C5AR1