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Complement C5 Antibody (eculizumab) [CoraFluor™ 1]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, Flow, Func
Clone
eculizumab
Clonality
Monoclonal
Host
Human
Conjugate
CoraFluor 1

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-28756AF350
Alexa Fluor 405
NBP3-28756AF405
Alexa Fluor 488
NBP3-28756AF488
Alexa Fluor 532
NBP3-28756AF532
Alexa Fluor 594
NBP3-28756AF594
Alexa Fluor 647
NBP3-28756AF647
Alexa Fluor 700
NBP3-28756AF700
Alexa Fluor 750
NBP3-28756AF750
Allophycocyanin
NBP3-28756APC
Biotin
NBP3-28756B
DyLight 350
NBP3-28756UV
DyLight 405
NBP3-28756V
DyLight 488
NBP3-28756G
DyLight 550
NBP3-28756R
DyLight 594
NBP3-28756DL594
DyLight 650
NBP3-28756C
DyLight 680
NBP3-28756FR
DyLight 755
NBP3-28756IR
FITC
NBP3-28756F
HRP
NBP3-28756H
Janelia Fluor 525
NBP3-28756JF525
Janelia Fluor 549
NBP3-28756JF549
Janelia Fluor 646
NBP3-28756JF646
Janelia Fluor 669
NBP3-28756JF669
PE
NBP3-28756PE
PerCP
NBP3-28756PCP
Unconjugated
NBP3-28756-100ug
mFluor Violet 450 SE
NBP3-28756MFV450
mFluor Violet 500 SE
NBP3-28756MFV500
mFluor Violet 610 SE
NBP3-28756MFV610
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Complement C5 Antibody (eculizumab) [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Additional Information
Recombinant Monoclonal Antibody
Immunogen
Complement C5
Isotype
IgG1
Clonality
Monoclonal
Host
Human
Gene
C5
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Functional
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for Complement C5 Antibody (eculizumab) [CoraFluor™ 1]

  • anaphylatoxin C5a analog
  • C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4
  • C5
  • complement C5
  • complement component 5
  • CPAMD4MGC142298
  • FLJ17816
  • FLJ17822

Background

C5 is synthesised in the liver as a single polypeptide chain. Before secretion the molecule is glycosylated and secreted into plasma as a 190kDa glycoprotein consisting of a disulphide linked alpha-chain (115kDa) and beta-chain (75kDa). C5 occurs in plasma at about 75mg/L. It is activated via either the classical or the alternative complement pathway, by protoelytic cleavage of C5a (11.5kDa) from the N-terminal of the alpha-chain. C5a is a potent anaphylotoxin and stimulates directed migration of neutrophils, eosinophils, basophils and monocytes. The other fragment, C5b,initiates the assembly of the membrane attack complex that mediates the cytolysis of viral and bacterial pathogens.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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CXCL10/IP-10/CRG-2
[HRP]
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N/A CXCL10/IP-10/CRG-2 [HRP]
N/A CXCL10/IP-10/CRG-2 [HRP]
(155 Publications)
Species: Hu
Applications: ELISA
ARHGAP4 Antibody
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PFDN4 Antibody -
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Immunocytochemistry/ Immunofluorescence PFDN4 Antibody - Azide and BSA Free
Immunocytochemistry/ Immunofluorescence PFDN4 Antibody - Azide and BSA Free
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Species: Hu, Mu, Rt
Applications: ICC/IF, WB
Complement
Component C9 Antibody
NBP2-15952
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Complement C5
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NBP3-28756CL1
Complement C5 Antibody (eculizumab) [CoraFluor™ 1]
Species: Hu
Applications: ELISA, Flow, Func

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol C5