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Recombinant Human CKS1 His Protein

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SDS-Page: Recombinant Human CKS1 Protein [NBP2-51527] - 15% SDS Page (3 ug)
SDS-Page: Recombinant Human CKS1 Protein [NBP2-51527] - 15% SDS Page (3 ug)

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
1 mg/ml

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Recombinant Human CKS1 His Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-79 of Human CKS1

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSHKQIY YSDKYDDEEF EYRHVMLPKD IAKLVPKTHL MSESEWRNLG VQQSQGWVHY MIHEPEPHIL LFRRPLPKKP KK
Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
CKS1B
Purity
>95%, by SDS-PAGE

Applications/Dilutions

Dilutions
  • SDS-Page
Theoretical MW
12 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20 mM Tris-HCl buffer (pH 8.0), 0.15 M NaCl, 20% glycerol, 1 mM DTT
Preservative
No Preservative
Concentration
1 mg/ml
Purity
>95%, by SDS-PAGE

Alternate Names for Recombinant Human CKS1 His Protein

  • CDC28 protein kinase 1
  • CDC28 protein kinase 1B
  • CDC28 protein kinase regulatory subunit 1B
  • cell division control protein CKS1
  • CKS-1
  • CKS1CDC2-associated protein CKS1
  • ckshs1
  • cyclin-dependent kinases regulatory subunit 1
  • NB4 apoptosis/differentiation related protein
  • PNAS-143
  • PNAS-16
  • PNAS-18

Background

CKS1B (Cyclin-dependent kinases regulatory subunit 1) is a 79 amino acid protein that binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. Depleting CKS1B in breast cancer cells has been shown to slow cell cycle progression and regulation of CKS1B may provide a potential cancer treatment option. Besides breast cancer, CKS1B plays a role in multiple myeloma, adenocarcinoma, mantle cell lymphoma , oral squamous cell carcinoma, squamous cell carcinoma, cholesteatoma, paracoccidioidomycosis, intrahepatic cholangiocarcinoma, hepatoblastoma, hepatocellular carcinoma, non-small cell lung carcinoma, gallbladder carcinoma, basal cell carcinoma, endometrial carcinoma, renal cell carcinoma and thyroid carcinoma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Recombinant Human
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Bioinformatics

Gene Symbol CKS1B