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Cited-2 Antibody (JA22) [PE]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ICC/IF, IHC
Clone
JA22
Clonality
Monoclonal
Host
Mouse
Conjugate
PE

Order Details

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Cited-2 Antibody (JA22) [PE] Summary

Immunogen
Human CITED 2 protein [UniProt# Q99967]
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CITED2
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Alternate Names for Cited-2 Antibody (JA22) [PE]

  • Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain2,cbp/p300-interacting transactivator 2
  • Cited2
  • Cited-2
  • MRG-1
  • MRG1melanocyte-specific gene 1-related gene 1
  • MSG1-related gene 1
  • MSG-related protein 1
  • P35srj

Background

CITED2 is a cAMP-responsive element-binding protein (CBP)/p300 interacting transcriptional modulator. CITED-2 has been proposed as a negative regulator for HIF-1 alpha, as it is thought to interfere with the binding of transcription factors HIF-1a and STAT2 to p300/CBP. Recruitment of CBP/p300 by HIF-1 is essential for the transcriptional response to hypoxia.

CITED 2 antibodies are useful tools for research on hypoxic response mechanisms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Cited-2 Antibody (NB100-136PE) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CITED2