Immunohistochemistry-Paraffin: Chorein Antibody [NBP1-85641] - Staining of human liver shows moderate cytoplasmic positivity in hepatocytes.
Immunohistochemistry-Paraffin: Chorein Antibody [NBP1-85641] - Staining of human duodenum shows moderate cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: Chorein Antibody [NBP1-85641] - Staining of human kidney shows strong cytoplasmic positivity in cells in tubules.
Immunohistochemistry-Paraffin: Chorein Antibody [NBP1-85641] - Staining of human testis shows strong cytoplasmic positivity in cells in seminiferous ducts.
This antibody was developed against Recombinant Protein corresponding to amino acids: RPPRFFNEDGVIRPYRLRDGTGNQMLQVMENGRFAKYKYFTHVMINKTDMLMITRRGVLFVTKGTFGQLTCEWQYSFDEFTKEPFIVHGRRLRIEAKERVKSVF
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
VPS13A
Purity
Immunogen affinity purified
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Mouse reactivity reported in the scientific literature (PMID: 29928881).
Packaging, Storage & Formulations
Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified
Alternate Names for Chorein Antibody
CHAC
chorea-acanthocytosis protein
vacuolar protein sorting 13 homolog A (S. cerevisiae)
vacuolar protein sorting 13A
Background
Chorein may control steps in the cycling of proteins through the trans-Golgi network to endosomes, lysosomes and the plasma membrane. Mutations in this gene cause the autosomal recessive disorder chorea-acanthocytosis. Alternative splicing of this gene results in multiple transcript variants.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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