Choline Acetyltransferase/ChAT Antibody [Biotin]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

ChAT catalyzes the production of the neurotransmitter acetylcholine (Ach), which is required for cholinergic neuron communication. It serves as a marker for functional cholinergic neurons in the central and peripheral nervous systems. At least six ChAT mRNAs encoding 69 kDa, 82 kDa and 74 kDa ChAT proteins have been identified. Compared to the 82 kDa form, 69 kDa ChAT lacks the N-terminal 118 amino acid extension containing a nuclear localization signal. As a result the 69 kDa ChAT is primarily localized to the cytoplasm. Human 69 kDa ChAT shares 86% amino acid sequence identity with the mouse or rat ChAT.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publication using BAF3447	Applications	Species
Swetha Vijayaraghavan, Azadeh Karami, Shahin Aeinehband, Homira Behbahani, Alf Grandien, Bo Nilsson et al. Regulated Extracellular Choline Acetyltransferase Activity— The Plausible Missing Link of the Distant Action of Acetylcholine in the Cholinergic Anti-Inflammatory Pathway PLoS ONE 2013-06-19 [PMID: 23840379]

Array BAF3447

• Choline Acetyltransferase/ChAT Antibodies
• Choline Acetyltransferase/ChAT ELISA Kits
• Choline Acetyltransferase/ChAT Kits
• Choline Acetyltransferase/ChAT Lysate
• Choline Acetyltransferase/ChAT Proteins