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CETP Antibody (2F1)

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Immunohistochemistry: CETP Antibody (2F1) [NBP3-15191] - IHC image of CETP antibody diluted at 1:115 and staining in paraffin-embedded human liver tissue. After dewaxing and hydration, antigen retrieval was mediated by ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, IHC
Clone
2F1
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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CETP Antibody (2F1) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthesized peptide derived from human CETP. UniProt ID (P11597).
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
CETP
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry 1:50-1:200

Packaging, Storage & Formulations

Storage
Store at -20 to -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4), 150mM NaCl, and 50% glycerol.
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for CETP Antibody (2F1)

  • BPIFF
  • CETP
  • cholesteryl ester transfer protein
  • cholesteryl ester transfer protein, plasma
  • HDLCQ10
  • Lipid Transfer Protein I

Background

It has been proposed that high density lipoproteins (HDLs) function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver. This mechanism, referred to as reverse cholesterol transport, is physiologically important because it maintains systemic cholesterol levels. CETP is responsible for neutral lipid transfer activity in plasma in numerous species. Since CETP is able to accelerate specifically the exchange of lipid components between pro- and anti-atherogenic lipoprotein fractions, it may be a key determinant of the global atherogenicity of the plasma lipoprotein profile and arises as a possible target in atherosclerosis prevention. CETP has an important role in reverse cholesterol transport and shaping and affecting the composition of plasma lipoproteins. In general elevated levels of CETP have been associated with increased risk of coronary heart disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CETP